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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Giancarlo Stanton# | 716 | 2011-2025 | |
| 2 | Albert Pujols | 588 | 2001-2020 | |
| 3 | Miguel Cabrera | 447 | 2004-2022 | |
| 4 | Mike Trout# | 426 | 2010-2025 | |
| 5 | Bryce Harper# | 422 | 2012-2025 | |
| 6 | Al Kaline | 399 | 1953-1974 | |
| 7 | Manny Machado# | 391 | 2015-2025 | |
| 8 | Ryan Howard | 371 | 2004-2015 | |
| 9 | Smith Smith | 351 | 2000-2017 | |
| 10 | Aramis Ramirez | 350 | 2000-2016 | |
| 11 | Evan Longoria | 346 | 2009-2023 | |
| 12 | Paul Goldschmidt# | 341 | 2012-2025 | |
| 12 | Joey Votto | 341 | 2007-2023 | |
| 14 | Edwin Encarnacion | 340 | 2006-2020 | |
| 15 | Nolan Arenado# | 336 | 2010-2025 | |
| 16 | Mark Teixeira | 328 | 2003-2017 | |
| 17 | Prince Fielder | 325 | 2006-2017 | |
| 18 | Aaron Judge# | 323 | 2017-2025 | |
| 19 | Brandon Belt# | 322 | 2012-2025 | |
| 20 | Joey Gallo# | 320 | 2017-2025 | |
| 21 | Adrian Gonzalez | 318 | 2005-2018 | |
| 22 | Kyle Schwarber# | 317 | 2015-2025 | |
| 23 | Curtis Granderson | 309 | 2006-2019 | |
| 24 | Adrian Beltre | 308 | 1999-2019 | |
| 25 | Anthony Rizzo# | 306 | 2011-2025 | |
| 26 | Freddie Freeman# | 302 | 2012-2025 | |
| 26 | Mark Reynolds | 302 | 2007-2018 | |
| 28 | Ryan Braun | 301 | 2008-2020 | |
| 29 | Justin Upton | 298 | 2007-2022 | |
| 30 | Nelson Cruz | 290 | 2006-2022 | |
| 31 | Carlos Santana# | 289 | 2010-2025 | |
| 32 | Matt Olson# | 285 | 2017-2025 | |
| 33 | Yoenis Cespedes | 281 | 2012-2020 | |
| 33 | Brian McCann | 281 | 2006-2021 | |
| 35 | J.D. Martinez# | 277 | 2012-2025 | |
| 36 | Robinson Cano | 276 | 2005-2022 | |
| 37 | Nick Castellanos# | 272 | 2014-2025 | |
| 37 | Yasmani Grandal# | 272 | 2016-2025 | |
| 39 | Chase Utley | 271 | 2004-2018 | |
| 40 | Victor Martinez | 269 | 2003-2018 | |
| 41 | Eugenio Suarez# | 268 | 2016-2025 | |
| 42 | Salvador Perez# | 266 | 2012-2025 | |
| 43 | Juan Soto# | 260 | 2019-2025 | |
| 44 | Josh Donaldson | 258 | 2011-2024 | |
| 45 | Joc Pederson# | 256 | 2012-2025 | |
| 46 | Francisco Lindor# | 254 | 2014-2025 | |
| 47 | Michael Conforto# | 253 | 2015-2025 | |
| 48 | Marcell Ozuna# | 252 | 2012-2025 | |
| 48 | George Springer# | 252 | 2015-2025 | |
| 50 | Ryan Zimmerman | 251 | 2006-2021 | |
| 51 | Matt Chapman# | 250 | 2015-2025 | |
| 51 | Justin Morneau | 250 | 2003-2017 | |
| 53 | Marcus Betts# | 247 | 2015-2025 | |
| 54 | Jay Bruce | 246 | 2008-2021 | |
| 55 | Gary Sanchez# | 245 | 2010-2025 | |
| 56 | Pete Alonso# | 241 | 2017-2025 | |
| 56 | Kyle Seager | 241 | 2010-2023 | |
| 56 | David Wright | 241 | 2005-2018 | |
| 59 | Mark Trumbo | 239 | 2010-2019 | |
| 60 | Mike Moustakas | 236 | 2012-2023 | |
| 61 | Randal Grichuk# | 234 | 2010-2025 | |
| 61 | Corey Seager# | 234 | 2016-2025 | |
| 63 | Matt Holliday | 233 | 2005-2018 | |
| 64 | Cody Bellinger# | 231 | 2018-2025 | |
| 64 | Andrew McCutchen# | 231 | 2009-2025 | |
| 66 | Daniel Murphy | 230 | 2009-2022 | |
| 67 | Jose Ramirez# | 229 | 2012-2025 | |
| 68 | Hunter Renfroe# | 224 | 2017-2025 | |
| 69 | Jorge Soler# | 223 | 2016-2025 | |
| 70 | Kris Bryant# | 221 | 2017-2025 | |
| 70 | Matt Kemp | 221 | 2007-2021 | |
| 72 | Rafael Devers# | 218 | 2019-2025 | |
| 72 | Max Muncy# | 218 | 2016-2025 | |
| 72 | Troy Tulowitzki | 218 | 2008-2019 | |
| 75 | Carlos Correa# | 216 | 2017-2025 | |
| 75 | Todd Frazier | 216 | 2010-2020 | |
| 77 | Max Kepler# | 214 | 2010-2025 | |
| 77 | Kendrys Morales | 214 | 2005-2018 | |
| 79 | Hanley Ramirez | 212 | 2006-2018 | |
| 80 | Eric Hosmer | 211 | 2009-2024 | |
| 81 | Chris Davis | 210 | 2007-2018 | |
| 81 | Mike Zunino# | 210 | 2016-2025 | |
| 83 | Josh Hamilton | 209 | 2008-2017 | |
| 83 | Adam Jones | 209 | 2008-2020 | |
| 83 | Nick Swisher | 209 | 2005-2016 | |
| 86 | Ian Kinsler | 207 | 2007-2019 | |
| 87 | Mike Napoli | 204 | 2005-2017 | |
| 88 | Jose Bautista | 203 | 1997-2019 | |
| 89 | Fernando Tatis Jr.# | 198 | 2020-2025 | |
| 90 | Asdrubal Cabrera | 195 | 2008-2022 | |
| 91 | Travis D'Arnaud# | 193 | 2010-2025 | |
| 91 | Adam Duvall# | 193 | 2014-2024 | |
| 91 | Domingo Santana# | 193 | 2010-2023 | |
| 94 | C.J. Cron# | 190 | 2014-2025 | |
| 94 | Rhys Hoskins# | 190 | 2015-2025 | |
| 96 | Jose Altuve# | 189 | 2012-2025 | |
| 97 | Ronald Acuna Jr.# | 187 | 2019-2025 | |
| 97 | Trea Turner# | 187 | 2015-2025 | |
| 99 | Coco Crisp | 186 | 2005-2017 | |
| 99 | Christian Yelich# | 186 | 2015-2025 |
