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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | WPCT | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Shane McClanahan# | .739 | 2023-2026 | |
| 2 | Pablo Lopez# | .681 | 2021-2026 | |
| 3 | Trevor Bauer | .670 | 2012-2023 | |
| 4 | Corbin Burnes# | .667 | 2020-2025 | |
| 5 | Sandy Koufax | .655 | 1955-1966 | |
| 6 | Shohei Ohtani# | .652 | 2018-2026 | |
| 7 | David Price | .651 | 2009-2023 | |
| 8 | Tarik Skubal# | .650 | 2022-2026 | |
| 9 | Matt Belisle | .647 | 2004-2018 | |
| 10 | Jeff Locke | .633 | 2011-2017 | |
| 11 | Jacob Degrom# | .631 | 2012-2026 | |
| 11 | Justin Verlander# | .631 | 2007-2026 | |
| 13 | Josh M. Johnson | .627 | 2006-2017 | |
| 14 | Walker Buehler# | .612 | 2019-2025 | |
| 15 | Chad Billingsley | .608 | 2007-2015 | |
| 16 | Lance McCullers Jr.# | .607 | 2016-2026 | |
| 16 | CC Sabathia | .607 | 2002-2020 | |
| 18 | Yu Darvish# | .606 | 2012-2026 | |
| 18 | Neftali Feliz | .606 | 2010-2018 | |
| 20 | Mat Latos | .603 | 2010-2016 | |
| 21 | Jose De Leon# | .600 | 2017-2022 | |
| 21 | Zac Gallen# | .600 | 2020-2026 | |
| 23 | Lucas Giolito# | .598 | 2016-2026 | |
| 24 | Collin McHugh | .593 | 2010-2024 | |
| 24 | Ubaldo Jimenez | .593 | 2010-2020 | |
| 24 | Max Scherzer# | .593 | 2009-2026 | |
| 27 | Aaron Nola# | .592 | 2015-2026 | |
| 28 | Michael Lorenzen# | .590 | 2018-2026 | |
| 29 | Bob Feller | .587 | 1947-1956 | |
| 29 | Yusei Kikuchi# | .587 | 2019-2026 | |
| 31 | Max Fried# | .586 | 2018-2026 | |
| 31 | Catfish Hunter | .586 | 1965-1976 | |
| 33 | Dylan Cease# | .583 | 2015-2026 | |
| 33 | Jake Peavy | .583 | 2002-2018 | |
| 33 | Freddy Peralta# | .583 | 2019-2026 | |
| 33 | Robbie Ray# | .583 | 2017-2026 | |
| 33 | Nathan Eovaldi# | .583 | 2012-2026 | |
| 38 | Andrew Miller | .582 | 2007-2020 | |
| 38 | Brad Ziegler | .582 | 2007-2018 | |
| 40 | Jerry Blevins | .581 | 2008-2018 | |
| 41 | Steve Matz# | .580 | 2010-2026 | |
| 41 | Bryse Wilson# | .580 | 2020-2026 | |
| 43 | Logan Webb# | .579 | 2015-2026 | |
| 44 | Nick Pivetta# | .573 | 2019-2026 | |
| 45 | Clayton Kershaw# | .572 | 2009-2025 | |
| 45 | Marcus Stroman# | .572 | 2015-2026 | |
| 47 | Danny Salazar | .571 | 2010-2021 | |
| 48 | Jake Odorizzi | .570 | 2012-2023 | |
| 48 | Tom Gorzelanny | .570 | 2007-2016 | |
| 50 | Matt Andriese | .566 | 2012-2023 | |
| 50 | Ian Kennedy | .566 | 2010-2022 | |
| 50 | Wily Peralta | .566 | 2012-2019 | |
| 53 | Tyler Glasnow# | .563 | 2017-2026 | |
| 53 | Steve Hamilton | .563 | 1961-1972 | |
| 55 | Joe Musgrove# | .562 | 2012-2026 | |
| 55 | Luis Severino# | .562 | 2016-2026 | |
| 55 | Tim Lincecum | .562 | 2009-2018 | |
| 55 | Stephen Strasburg | .562 | 2010-2025 | |
| 59 | Kyle Gibson# | .561 | 2010-2025 | |
| 59 | Matt Strahm# | .561 | 2016-2026 | |
| 59 | Gerrit Cole# | .561 | 2012-2026 | |
| 59 | Jesse Chavez# | .561 | 2010-2025 | |
| 63 | Carlos Rodon# | .559 | 2015-2026 | |
| 63 | Scott Baker | .559 | 2006-2014 | |
| 63 | Shane Bieber# | .559 | 2020-2026 | |
| 66 | Santiago Casilla | .557 | 2005-2017 | |
| 67 | Oliver Perez | .556 | 2003-2022 | |
| 67 | Jarrod Parker | .556 | 2012-2015 | |
| 69 | Brandon Woodruff# | .555 | 2015-2026 | |
| 70 | Joe Nathan | .553 | 2000-2016 | |
| 70 | Joe Smith | .553 | 2008-2022 | |
| 72 | Andrew Cashner | .551 | 2011-2020 | |
| 72 | Smith Smith | .551 | 2004-2017 | |
| 74 | Darren O'Day | .548 | 2010-2022 | |
| 75 | Johnny Cueto | .547 | 2010-2023 | |
| 75 | Matt Cain | .547 | 2006-2019 | |
| 77 | Framber Valdez# | .545 | 2022-2026 | |
| 78 | German Marquez# | .544 | 2018-2025 | |
| 79 | Ricky Nolasco | .543 | 2007-2017 | |
| 79 | Adam Wainwright | .543 | 2004-2023 | |
| 79 | Corey Kluber | .543 | 2011-2023 | |
| 82 | David Robertson# | .542 | 2010-2026 | |
| 82 | Felix Hernandez | .542 | 2005-2021 | |
| 82 | Jon Lester | .542 | 2007-2021 | |
| 85 | Rich Harden | .541 | 2004-2013 | |
| 85 | Chris Sale# | .541 | 2011-2026 | |
| 87 | Justin Masterson | .540 | 2010-2016 | |
| 88 | Larry Dierker | .539 | 1964-1976 | |
| 88 | Jose Berrios# | .539 | 2016-2026 | |
| 90 | Matthew Boyd# | .538 | 2019-2026 | |
| 90 | Zack Wheeler# | .538 | 2010-2026 | |
| 90 | Cole Hamels | .538 | 2007-2022 | |
| 93 | Matt Harvey | .535 | 2014-2021 | |
| 94 | Johnny Antonelli | .534 | 1948-1961 | |
| 95 | Andrew Heaney# | .532 | 2018-2026 | |
| 95 | Chris Paddack# | .532 | 2020-2025 | |
| 97 | Neal Cotts | .531 | 2005-2016 | |
| 97 | Jeff Samardzija | .531 | 2010-2020 | |
| 97 | Ranger Suarez# | .531 | 2020-2026 | |
| 97 | Blake Snell# | .531 | 2012-2026 |
