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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | BB | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | CC Sabathia | 996 | 2002-2020 | |
| 2 | Smith Smith | 995 | 2006-2020 | |
| 3 | Felix Hernandez | 878 | 2005-2021 | |
| 4 | Scott Kazmir | 870 | 2005-2018 | |
| 5 | Bartolo Colon | 847 | 1997-2019 | |
| 6 | Lance Lynn# | 844 | 2010-2025 | |
| 7 | Catfish Hunter | 838 | 1965-1976 | |
| 8 | Adam Wainwright | 822 | 2004-2023 | |
| 9 | Sandy Koufax | 817 | 1955-1966 | |
| 10 | Charlie Morton# | 816 | 2010-2025 | |
| 11 | Gio Gonzalez | 809 | 2010-2022 | |
| 12 | J.J. Franco | 804 | 1999-2014 | |
| 13 | Josh M. Johnson | 801 | 2006-2017 | |
| 14 | Clayton Kershaw# | 797 | 2009-2025 | |
| 15 | Matt Cain | 793 | 2006-2019 | |
| 16 | Edinson Volquez | 788 | 2008-2020 | |
| 17 | Cole Hamels | 776 | 2007-2022 | |
| 18 | Justin Verlander# | 772 | 2007-2025 | |
| 19 | Zack Wheeler# | 771 | 2010-2025 | |
| 20 | Rich Hill# | 770 | 2006-2023 | |
| 21 | Jake Peavy | 769 | 2002-2018 | |
| 22 | Bob Feller | 761 | 1947-1956 | |
| 23 | John Lackey | 753 | 2003-2017 | |
| 24 | Max Scherzer# | 722 | 2009-2025 | |
| 25 | Jon Lester | 717 | 2007-2021 | |
| 26 | Brett Myers | 706 | 2003-2014 | |
| 27 | Chris Young | 700 | 2004-2016 | |
| 28 | Larry Dierker | 695 | 1964-1976 | |
| 29 | Johnny Antonelli | 687 | 1948-1961 | |
| 30 | Matt Moore# | 678 | 2012-2025 | |
| 31 | Anibal Sanchez | 677 | 2007-2021 | |
| 32 | Jake Arrieta | 668 | 2011-2022 | |
| 32 | Aaron Harang | 668 | 2002-2015 | |
| 34 | Johnny Cueto | 667 | 2010-2023 | |
| 34 | Stephen Strasburg# | 667 | 2010-2025 | |
| 36 | Smith Smith | 656 | 2002-2017 | |
| 37 | Lance McCullers Jr.# | 643 | 2016-2025 | |
| 38 | Yu Darvish# | 641 | 2012-2025 | |
| 39 | Rich Harden | 633 | 2004-2013 | |
| 40 | Clay Buchholz | 630 | 2008-2020 | |
| 41 | Jon Gray# | 613 | 2015-2025 | |
| 42 | John Danks | 611 | 2008-2018 | |
| 43 | Jose Quintana# | 610 | 2013-2025 | |
| 44 | James Happ | 606 | 2009-2022 | |
| 45 | Ubaldo Jimenez | 603 | 2010-2020 | |
| 46 | Brandon McCarthy | 595 | 2006-2019 | |
| 46 | Oliver Perez | 595 | 2003-2022 | |
| 48 | David Price | 592 | 2009-2023 | |
| 49 | Gavin Floyd | 586 | 2005-2017 | |
| 50 | Garrett Richards | 584 | 2012-2022 | |
| 51 | Michael Pineda | 583 | 2011-2023 | |
| 52 | Alex Cobb# | 579 | 2012-2025 | |
| 53 | Chris Archer | 571 | 2012-2023 | |
| 53 | Drew Pomeranz | 571 | 2012-2023 | |
| 55 | Danny Duffy | 568 | 2012-2022 | |
| 56 | Julio Teheran | 566 | 2011-2022 | |
| 57 | James Paxton# | 557 | 2014-2025 | |
| 58 | Billy O'Dell | 556 | 1954-1967 | |
| 59 | Jered Weaver | 554 | 2007-2017 | |
| 60 | Yovani Gallardo | 548 | 2008-2018 | |
| 60 | Michael Wacha# | 548 | 2015-2025 | |
| 62 | Wade Miley# | 547 | 2010-2024 | |
| 63 | Ian Kennedy | 543 | 2010-2022 | |
| 64 | Tim Lincecum | 542 | 2009-2018 | |
| 65 | Smith Smith | 541 | 2004-2017 | |
| 66 | Danny Salazar | 540 | 2010-2021 | |
| 67 | Gerrit Cole# | 531 | 2012-2025 | |
| 68 | Chris Sale# | 530 | 2011-2025 | |
| 69 | Brandon Morrow | 529 | 2009-2020 | |
| 70 | James Shields | 528 | 2007-2019 | |
| 71 | Chad Billingsley | 526 | 2007-2015 | |
| 71 | Kyle Gibson# | 526 | 2010-2024 | |
| 73 | Tyson Ross | 521 | 2012-2019 | |
| 74 | Smith Smith | 517 | 2008-2017 | |
| 75 | Paul Maholm | 514 | 2006-2015 | |
| 76 | Ervin Santana | 511 | 2002-2019 | |
| 77 | Blake Snell# | 510 | 2012-2025 | |
| 78 | Brett Anderson | 507 | 2010-2021 | |
| 79 | Sonny Gray# | 506 | 2012-2025 | |
| 80 | Jeff Samardzija | 503 | 2010-2020 | |
| 81 | Homer Bailey | 498 | 2009-2020 | |
| 82 | Smith Smith | 493 | 2002-2018 | |
| 83 | Kevin Gausman# | 486 | 2013-2025 | |
| 84 | Brandon Woodruff# | 485 | 2015-2025 | |
| 85 | Lucas Giolito# | 483 | 2016-2025 | |
| 86 | Robbie Ray# | 481 | 2017-2025 | |
| 87 | Craig Kimbrel# | 480 | 2011-2025 | |
| 88 | Neftali Feliz | 479 | 2010-2018 | |
| 88 | Jordan Zimmermann | 479 | 2010-2021 | |
| 90 | Jameson Taillon# | 478 | 2014-2025 | |
| 91 | German Marquez# | 476 | 2018-2025 | |
| 92 | Carlos Rodon# | 475 | 2015-2025 | |
| 93 | Ryan Madson | 473 | 2003-2019 | |
| 94 | Tyler Mahle# | 472 | 2017-2025 | |
| 95 | Joe Blanton | 469 | 2006-2017 | |
| 96 | Trevor Rosenthal | 468 | 2010-2023 | |
| 97 | Dylan Bundy | 463 | 2012-2023 | |
| 98 | Tyler Anderson# | 462 | 2012-2025 | |
| 99 | Derek Holland | 461 | 2010-2019 | |
| 100 | Mike Minor | 460 | 2010-2023 |
