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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Paul Goldschmidt# | 330 | 2012-2025 | |
| 2 | Anthony Rizzo# | 306 | 2011-2025 | |
| 3 | Freddie Freeman# | 302 | 2012-2025 | |
| 4 | Brandon Belt# | 286 | 2012-2025 | |
| 5 | Joey Votto | 282 | 2007-2023 | |
| 6 | Albert Pujols | 239 | 2001-2020 | |
| 7 | Adrian Gonzalez | 231 | 2005-2018 | |
| 8 | Eric Hosmer | 211 | 2009-2024 | |
| 9 | Chris Davis | 205 | 2007-2018 | |
| 10 | Matt Olson# | 204 | 2017-2025 | |
| 11 | Pete Alonso# | 192 | 2017-2025 | |
| 11 | Mark Trumbo | 192 | 2010-2019 | |
| 13 | Mark Teixeira | 184 | 2003-2017 | |
| 14 | Prince Fielder | 169 | 2006-2017 | |
| 15 | Kendrys Morales | 168 | 2005-2018 | |
| 16 | Miguel Cabrera | 163 | 2004-2022 | |
| 17 | Justin Morneau | 153 | 2003-2017 | |
| 17 | Justin Smoak | 153 | 2012-2020 | |
| 19 | Edwin Encarnacion | 152 | 2006-2020 | |
| 20 | C.J. Cron# | 146 | 2014-2025 | |
| 21 | Matt Adams | 140 | 2010-2020 | |
| 22 | Rhys Hoskins# | 136 | 2015-2025 | |
| 23 | Josh Bell# | 131 | 2012-2025 | |
| 24 | Christian Walker# | 129 | 2016-2025 | |
| 25 | Justin Bour | 124 | 2016-2021 | |
| 25 | Ryan Howard | 124 | 2004-2015 | |
| 27 | Carlos Santana# | 118 | 2010-2025 | |
| 28 | Daniel Murphy | 107 | 2009-2022 | |
| 29 | Travis Shaw | 106 | 2016-2021 | |
| 30 | Nathaniel Lowe# | 105 | 2017-2025 | |
| 31 | Garrett Jones | 104 | 2007-2016 | |
| 32 | Gregory Bird | 98 | 2012-2021 | |
| 32 | Jake Lamb | 98 | 2015-2021 | |
| 32 | Mike Napoli | 98 | 2005-2017 | |
| 35 | Jesus Aguilar | 97 | 2012-2023 | |
| 36 | James Loney | 94 | 2007-2017 | |
| 37 | Ryan Mountcastle# | 93 | 2021-2025 | |
| 38 | Mitch Moreland | 91 | 2011-2019 | |
| 39 | Trey Mancini# | 85 | 2018-2023 | |
| 40 | Logan Morrison | 83 | 2011-2022 | |
| 41 | Cody Bellinger# | 81 | 2018-2025 | |
| 42 | Vladimir Guerrero Jr.# | 78 | 2019-2025 | |
| 43 | Max Muncy# | 75 | 2016-2025 | |
| 44 | Edwin Rios# | 73 | 2022-2025 | |
| 45 | Jim Spencer | 72 | 1968-1976 | |
| 45 | Rowdy Tellez# | 72 | 2019-2025 | |
| 47 | Ryan Zimmerman | 71 | 2006-2021 | |
| 48 | Josh Naylor# | 69 | 2020-2025 | |
| 48 | Gaby Sanchez | 69 | 2009-2016 | |
| 48 | Luke Voit# | 69 | 2019-2023 | |
| 51 | Triston Casas# | 68 | 2023-2025 | |
| 52 | Jake Burger# | 67 | 2021-2024 | |
| 53 | Victor Martinez | 66 | 2003-2018 | |
| 54 | Sean Bouchard# | 64 | 2023-2025 | |
| 55 | Ike Davis | 63 | 2011-2016 | |
| 56 | Ty France# | 61 | 2019-2025 | |
| 56 | Joey Gallo# | 61 | 2017-2025 | |
| 56 | Dominic Smith# | 61 | 2018-2023 | |
| 59 | Adam Lind | 59 | 2007-2018 | |
| 60 | Casey Kotchman | 56 | 2005-2014 | |
| 61 | Allen Craig | 54 | 2010-2015 | |
| 62 | Marwin Gonzalez | 52 | 2015-2021 | |
| 62 | Nick Swisher | 52 | 2005-2016 | |
| 64 | Mike Carp | 50 | 2010-2015 | |
| 64 | Lucas Duda | 50 | 2011-2018 | |
| 64 | Abraham Toro# | 50 | 2020-2025 | |
| 64 | Brett Wallace | 50 | 2010-2017 | |
| 68 | Nick Pratto# | 49 | 2023-2025 | |
| 69 | Ryan Braun | 47 | 2008-2020 | |
| 69 | Rafael Devers# | 47 | 2019-2025 | |
| 69 | Vinnie Pasquantino# | 47 | 2023-2025 | |
| 72 | Billy Butler | 46 | 2007-2017 | |
| 72 | Adam Duvall# | 46 | 2014-2024 | |
| 72 | Wilmer Flores# | 46 | 2010-2024 | |
| 75 | Ryon Healy | 44 | 2017-2020 | |
| 76 | Yonder Alonso | 42 | 2012-2019 | |
| 76 | Ryan O'Hearn# | 42 | 2015-2025 | |
| 78 | Ronald Guzman# | 39 | 2015-2020 | |
| 79 | Bradley Miller | 37 | 2014-2022 | |
| 80 | Jared Walsh# | 35 | 2022-2024 | |
| 81 | Kyle Blanks | 34 | 2010-2017 | |
| 81 | Chris Carter | 34 | 2009-2017 | |
| 83 | Nelson Cruz | 33 | 2006-2022 | |
| 83 | Ryan Noda# | 33 | 2022-2025 | |
| 83 | Bobby Seymour# | 33 | 2025-2025 | |
| 83 | Juan Yepez# | 33 | 2022-2025 | |
| 87 | Edouard Julien# | 32 | 2024-2025 | |
| 87 | Brandon Lowe# | 32 | 2021-2025 | |
| 87 | Jefry Marte | 32 | 2010-2019 | |
| 87 | Pablo Sandoval | 32 | 2009-2021 | |
| 87 | Mark Vientos# | 32 | 2024-2025 | |
| 92 | Joe Mauer | 30 | 2004-2018 | |
| 92 | Evan White# | 30 | 2020-2023 | |
| 94 | Kris Bryant# | 29 | 2017-2025 | |
| 94 | Tyler White | 29 | 2018-2020 | |
| 96 | Matt Skole | 28 | 2012-2017 | |
| 96 | Spencer Torkelson# | 28 | 2024-2025 | |
| 98 | Jeimer Candelario# | 27 | 2017-2025 | |
| 98 | Casey McGehee | 27 | 2009-2015 | |
| 100 | Miguel Andujar# | 26 | 2017-2025 |
