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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Robinson Cano | 215 | 2005-2022 | |
| 2 | Jose Altuve# | 179 | 2012-2025 | |
| 3 | Neil Walker | 165 | 2009-2020 | |
| 4 | Brian Dozier | 156 | 2010-2020 | |
| 5 | Chase Utley | 149 | 2004-2018 | |
| 6 | Ian Kinsler | 137 | 2007-2019 | |
| 7 | Dustin Pedroia | 118 | 2007-2019 | |
| 8 | Jason Kipnis | 114 | 2011-2021 | |
| 9 | Ozzie Albies# | 109 | 2019-2025 | |
| 10 | Asdrubal Cabrera | 107 | 2008-2022 | |
| 11 | Jurickson Profar# | 102 | 2010-2025 | |
| 12 | Brandon Lowe# | 101 | 2021-2025 | |
| 12 | Gleyber Torres# | 101 | 2019-2025 | |
| 14 | D.J. LeMahieu# | 96 | 2010-2025 | |
| 15 | Brandon Phillips | 91 | 2003-2018 | |
| 16 | Howie Kendrick | 90 | 2005-2021 | |
| 17 | Kelly Johnson | 89 | 2006-2016 | |
| 18 | Rougned Odor | 87 | 2012-2023 | |
| 19 | Jeff McNeil# | 86 | 2019-2025 | |
| 19 | Jorge Polanco# | 86 | 2010-2025 | |
| 21 | Ketel Marte# | 81 | 2017-2025 | |
| 22 | Cavan Biggio# | 80 | 2020-2025 | |
| 23 | Rickie Weeks Jr. | 78 | 2007-2015 | |
| 24 | Starlin Castro | 76 | 2011-2023 | |
| 24 | Martin Prado | 76 | 2006-2018 | |
| 26 | Devon Travis | 75 | 2016-2020 | |
| 27 | Aaron Hill | 70 | 2005-2016 | |
| 27 | Ben Zobrist | 70 | 2007-2020 | |
| 29 | Tony Taylor | 64 | 1958-1976 | |
| 29 | Luis Urias# | 64 | 2019-2025 | |
| 31 | Brandon Drury# | 58 | 2014-2025 | |
| 31 | Scooter Gennett | 58 | 2010-2020 | |
| 31 | Cesar Hernandez | 58 | 2012-2022 | |
| 34 | Willie Calhoun# | 55 | 2020-2024 | |
| 35 | Sean Rodriguez | 54 | 2008-2018 | |
| 36 | Jazz Chisholm# | 51 | 2022-2025 | |
| 37 | Rodolfo Castro# | 50 | 2022-2024 | |
| 37 | Anthony Volpe# | 50 | 2023-2025 | |
| 39 | Aledmys Diaz | 49 | 2015-2023 | |
| 40 | Luis Garcia Jr.# | 48 | 2022-2025 | |
| 41 | Thairo Estrada# | 47 | 2018-2025 | |
| 41 | Jed Lowrie | 47 | 2008-2020 | |
| 43 | Niko Goodrum# | 46 | 2012-2022 | |
| 44 | Javier Baez# | 44 | 2012-2025 | |
| 45 | Jake Cronenworth# | 43 | 2021-2025 | |
| 46 | Brendan Rodgers# | 42 | 2021-2025 | |
| 47 | Ha-Seong Kim# | 41 | 2021-2025 | |
| 47 | Tommy La Stella | 41 | 2012-2022 | |
| 47 | Eduardo Nunez | 41 | 2011-2022 | |
| 50 | Logan Forsythe | 40 | 2012-2019 | |
| 50 | Marcus Semien# | 40 | 2015-2025 | |
| 50 | Chris Taylor# | 40 | 2016-2025 | |
| 53 | Dustin Ackley | 38 | 2012-2017 | |
| 53 | Scott Hairston | 38 | 2005-2014 | |
| 53 | Enrique Hernandez# | 38 | 2010-2024 | |
| 56 | Romy Gonzalez# | 37 | 2022-2025 | |
| 56 | Jose Pirela# | 37 | 2010-2020 | |
| 58 | Freddy Galvis | 36 | 2012-2023 | |
| 58 | Ian Happ# | 36 | 2018-2025 | |
| 58 | Joe Panik | 36 | 2012-2021 | |
| 61 | Whit Merrifield# | 35 | 2017-2025 | |
| 61 | Christopher Morel# | 35 | 2023-2025 | |
| 63 | Jonathan India# | 34 | 2022-2025 | |
| 63 | Jose Ramirez# | 34 | 2012-2025 | |
| 65 | Christian Arroyo# | 33 | 2017-2025 | |
| 66 | Danny Espinosa | 32 | 2012-2017 | |
| 67 | Michael Chavis# | 31 | 2015-2022 | |
| 67 | Drew Robinson | 31 | 2012-2019 | |
| 67 | Trea Turner# | 31 | 2015-2025 | |
| 70 | Davis Schneider# | 30 | 2024-2025 | |
| 70 | Juan Uribe | 30 | 2002-2017 | |
| 72 | Keston Hiura# | 29 | 2020-2025 | |
| 72 | Josh Rojas# | 29 | 2021-2025 | |
| 74 | Gordon Beckham | 28 | 2010-2019 | |
| 75 | Franklin Barreto# | 27 | 2012-2021 | |
| 76 | Ezequiel Duran# | 26 | 2022-2025 | |
| 76 | Nolan Gorman# | 26 | 2022-2025 | |
| 76 | Brock Holt | 26 | 2010-2020 | |
| 76 | Joey Wendle# | 26 | 2016-2025 | |
| 80 | Charlie Culberson | 25 | 2012-2022 | |
| 80 | Yoan Moncada# | 25 | 2020-2025 | |
| 80 | Kevin Newman# | 25 | 2018-2023 | |
| 80 | Jonathan Villar | 25 | 2014-2022 | |
| 84 | Tony Kemp | 24 | 2017-2023 | |
| 84 | Luis Rengifo# | 24 | 2022-2025 | |
| 86 | Alexander Guerrero | 23 | 2014-2016 | |
| 86 | Hector Olivera | 23 | 2015-2017 | |
| 88 | Willi Castro# | 22 | 2021-2025 | |
| 88 | Chris Owings# | 22 | 2010-2019 | |
| 88 | Ezequiel Tovar# | 22 | 2023-2025 | |
| 91 | Everth Cabrera | 21 | 2010-2017 | |
| 91 | Derek Dietrich | 21 | 2012-2022 | |
| 93 | Yu Chang# | 20 | 2019-2025 | |
| 93 | Daniel Descalso | 20 | 2010-2020 | |
| 93 | Jordan Westburg# | 20 | 2024-2025 | |
| 96 | Zach Neto# | 19 | 2023-2025 | |
| 96 | Pat Valaika | 19 | 2018-2021 | |
| 98 | Isan Diaz# | 18 | 2015-2024 | |
| 98 | Jonathan Fernandez | 18 | 2010-2011 | |
| 98 | Daniel Robertson# | 18 | 2017-2022 |
