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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Mike Trout# | 317 | 2010-2025 | |
| 2 | Aaron Hicks# | 150 | 2012-2024 | |
| 3 | Byron Buxton# | 138 | 2017-2025 | |
| 4 | Marcus Betts# | 125 | 2015-2025 | |
| 5 | Joc Pederson# | 119 | 2012-2025 | |
| 6 | George Springer# | 117 | 2015-2025 | |
| 7 | Kevin Kiermaier# | 115 | 2014-2024 | |
| 8 | Trent Grisham# | 114 | 2020-2025 | |
| 9 | Matt Kemp | 103 | 2007-2021 | |
| 9 | Chris B. Young | 103 | 2006-2018 | |
| 11 | Curtis Granderson | 102 | 2006-2019 | |
| 12 | Harrison Bader# | 100 | 2018-2025 | |
| 13 | Cody Bellinger# | 98 | 2018-2025 | |
| 14 | Adam Jones | 97 | 2008-2020 | |
| 15 | A.J. Pollock | 94 | 2010-2023 | |
| 16 | Carlos Gomez | 93 | 2009-2019 | |
| 17 | Andrew McCutchen# | 92 | 2009-2025 | |
| 17 | Luis Robert Jr.# | 92 | 2021-2025 | |
| 19 | Al Kaline | 90 | 1953-1974 | |
| 20 | Tommy Pham# | 86 | 2010-2025 | |
| 21 | Ramon Laureano# | 85 | 2015-2025 | |
| 22 | Coco Crisp | 84 | 2005-2017 | |
| 23 | Dexter Fowler | 80 | 2010-2020 | |
| 24 | Bryce Harper# | 78 | 2012-2025 | |
| 25 | Keon Broxton | 77 | 2010-2020 | |
| 26 | Lorenzo Cain | 76 | 2011-2022 | |
| 26 | Randal Grichuk# | 76 | 2010-2025 | |
| 28 | Kevin Pillar | 75 | 2012-2023 | |
| 28 | Julio Rodriguez# | 75 | 2022-2025 | |
| 28 | Michael A. Taylor# | 75 | 2010-2025 | |
| 31 | Jacoby Ellsbury | 74 | 2009-2019 | |
| 32 | Clint Frazier | 68 | 2018-2022 | |
| 32 | Grady Sizemore | 68 | 2005-2016 | |
| 34 | Melvin Upton Jr. | 65 | 2005-2017 | |
| 35 | Charlie Blackmon# | 64 | 2012-2025 | |
| 36 | Aaron Altherr | 62 | 2015-2019 | |
| 36 | Andrew Benintendi# | 62 | 2018-2025 | |
| 36 | Denard Span | 62 | 2009-2019 | |
| 39 | Cameron Maybin | 61 | 2009-2020 | |
| 39 | Cedric Mullins# | 61 | 2019-2025 | |
| 41 | Brett Gardner | 58 | 2007-2021 | |
| 41 | Mickey Moniak# | 58 | 2023-2025 | |
| 43 | Jason Heyward# | 57 | 2011-2025 | |
| 43 | Colby Rasmus | 57 | 2010-2019 | |
| 45 | Manuel Margot# | 56 | 2012-2025 | |
| 46 | Angel Pagan | 55 | 2006-2017 | |
| 47 | Shin-Soo Choo | 54 | 2006-2020 | |
| 47 | Jake Meyers# | 54 | 2022-2025 | |
| 49 | Ronald Acuna Jr.# | 53 | 2019-2025 | |
| 50 | Shane Victorino | 52 | 2006-2016 | |
| 51 | Chris Heisey | 51 | 2010-2017 | |
| 52 | Odubel Herrera | 46 | 2012-2023 | |
| 53 | Starling Marte# | 45 | 2014-2025 | |
| 54 | Jake Marisnick | 44 | 2010-2021 | |
| 55 | Desmond Jennings | 41 | 2010-2016 | |
| 56 | Austin Jackson | 40 | 2010-2018 | |
| 57 | Juan Lagares | 37 | 2010-2020 | |
| 57 | Drew Stubbs | 37 | 2010-2017 | |
| 59 | Leody Taveras# | 36 | 2021-2025 | |
| 60 | Jo Adell# | 35 | 2021-2025 | |
| 60 | Kyle Parker | 35 | 2014-2016 | |
| 62 | Brandon Nimmo# | 34 | 2012-2025 | |
| 63 | Peter Bourjos | 32 | 2010-2016 | |
| 63 | Ketel Marte# | 32 | 2017-2025 | |
| 63 | Leonys Martin | 32 | 2016-2020 | |
| 66 | Michael Harris II# | 31 | 2023-2025 | |
| 66 | Smith Smith | 31 | 2000-2017 | |
| 66 | Lane Thomas# | 31 | 2015-2025 | |
| 69 | Albert Almora# | 30 | 2018-2021 | |
| 70 | Austin Meadows# | 29 | 2019-2025 | |
| 71 | Gregor Blanco | 28 | 2007-2018 | |
| 71 | Carl Crawford | 28 | 2004-2017 | |
| 71 | Derek Hill# | 28 | 2015-2025 | |
| 71 | Brandon Marsh# | 28 | 2022-2025 | |
| 71 | Tyler O'Neill# | 28 | 2018-2025 | |
| 71 | Mike Tauchman# | 28 | 2020-2025 | |
| 71 | Alek Thomas# | 28 | 2023-2025 | |
| 78 | Brian Goodwin | 27 | 2012-2021 | |
| 78 | Kyle Isbel# | 27 | 2023-2025 | |
| 78 | Ryan Kalish | 27 | 2010-2018 | |
| 78 | Smith Smith | 27 | 2004-2016 | |
| 78 | Ryan Sweeney | 27 | 2007-2018 | |
| 78 | Daulton Varsho# | 27 | 2021-2024 | |
| 84 | Franklin Gutierrez | 25 | 2008-2017 | |
| 84 | Garrett Hampson# | 25 | 2020-2025 | |
| 84 | Rafael Ortega# | 25 | 2012-2024 | |
| 84 | Victor Robles# | 25 | 2020-2025 | |
| 84 | Chris Taylor# | 25 | 2016-2025 | |
| 84 | Taylor Trammell# | 25 | 2021-2025 | |
| 90 | Shogo Akiyama | 24 | 2020-2022 | |
| 90 | Michael Brantley | 24 | 2009-2024 | |
| 90 | Jay Bruce | 24 | 2008-2021 | |
| 90 | Adam Eaton | 24 | 2012-2023 | |
| 90 | Josh Hamilton | 24 | 2008-2017 | |
| 90 | Jack Suwinski# | 24 | 2023-2025 | |
| 96 | Rajai Davis | 23 | 2006-2019 | |
| 97 | Greg Allen# | 22 | 2015-2024 | |
| 97 | Jesus Sanchez# | 22 | 2021-2025 | |
| 97 | Domingo Santana# | 22 | 2010-2023 | |
| 97 | Jose Siri# | 22 | 2019-2025 |
