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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | WPCT | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Jeurys Familia | 1.000 | 2010-2022 | |
| 1 | Mat Latos | 1.000 | 2010-2016 | |
| 1 | Charlie Morton# | 1.000 | 2010-2025 | |
| 1 | Jon Niese | 1.000 | 2009-2016 | |
| 1 | Joe Ryan# | 1.000 | 2022-2025 | |
| 1 | Tarik Skubal# | 1.000 | 2022-2025 | |
| 7 | Carlos Carrasco | .875 | 2010-2023 | |
| 8 | Madison Bumgarner | .800 | 2011-2023 | |
| 8 | Jacob Degrom# | .800 | 2012-2025 | |
| 10 | Gio Gonzalez | .750 | 2010-2022 | |
| 10 | Jose Leclerc# | .750 | 2018-2025 | |
| 10 | Miles Mikolas# | .750 | 2010-2025 | |
| 10 | Joe Musgrove# | .750 | 2012-2025 | |
| 10 | Jose Quintana# | .750 | 2013-2025 | |
| 15 | Max Scherzer# | .733 | 2009-2025 | |
| 16 | Pablo Lopez# | .714 | 2021-2025 | |
| 16 | Shane McClanahan# | .714 | 2023-2025 | |
| 18 | Homer Bailey | .667 | 2009-2020 | |
| 18 | Catfish Hunter | .667 | 1965-1976 | |
| 18 | Chris Jones | .667 | 2010-2012 | |
| 18 | Craig Kimbrel# | .667 | 2011-2025 | |
| 18 | Lance McCullers Jr.# | .667 | 2016-2025 | |
| 18 | Jake Odorizzi | .667 | 2012-2023 | |
| 18 | Blake Snell# | .667 | 2012-2025 | |
| 18 | Justin Souza | .667 | 2012-2012 | |
| 26 | Aaron Nola# | .615 | 2015-2025 | |
| 27 | Matthew Boyd# | .600 | 2019-2025 | |
| 27 | Wade Davis | .600 | 2009-2020 | |
| 27 | Ross Detwiler | .600 | 2011-2023 | |
| 27 | Kyle Hendricks# | .600 | 2016-2024 | |
| 27 | Merrill Kelly# | .600 | 2019-2025 | |
| 27 | Clayton Kershaw# | .600 | 2009-2025 | |
| 27 | Carlos Rodon# | .600 | 2015-2025 | |
| 27 | Logan Webb# | .600 | 2015-2025 | |
| 35 | Corbin Burnes# | .571 | 2020-2025 | |
| 35 | Corey Kluber | .571 | 2011-2023 | |
| 35 | Sandy Koufax | .571 | 1955-1966 | |
| 38 | Gerrit Cole# | .556 | 2012-2025 | |
| 39 | Chris Archer | .500 | 2012-2023 | |
| 39 | Trevor Bauer | .500 | 2012-2023 | |
| 39 | Yu Darvish# | .500 | 2012-2025 | |
| 39 | Zac Gallen# | .500 | 2020-2025 | |
| 39 | Derek Holland | .500 | 2010-2019 | |
| 39 | Tyler Mahle# | .500 | 2017-2025 | |
| 39 | Shohei Ohtani# | .500 | 2018-2025 | |
| 39 | Michael Pineda | .500 | 2011-2023 | |
| 39 | Ryan Pressley | .500 | 2010-2012 | |
| 39 | David Price | .500 | 2009-2023 | |
| 39 | Chris Sale# | .500 | 2011-2025 | |
| 39 | Smith Smith | .500 | 2004-2017 | |
| 39 | Stephen Strasburg# | .500 | 2010-2025 | |
| 39 | Marcus Stroman# | .500 | 2015-2025 | |
| 39 | Adam Wainwright | .500 | 2004-2023 | |
| 39 | Zack Wheeler# | .500 | 2010-2025 | |
| 55 | Walker Buehler# | .429 | 2019-2025 | |
| 55 | Julio Urias# | .429 | 2018-2025 | |
| 57 | Hyun-Jin Ryu | .400 | 2013-2023 | |
| 57 | Edinson Volquez | .400 | 2008-2020 | |
| 59 | Justin Verlander# | .385 | 2007-2025 | |
| 60 | Johnny Cueto | .333 | 2010-2023 | |
| 61 | Dellin Betances | .250 | 2011-2021 | |
| 61 | Nathan Eovaldi# | .250 | 2012-2025 | |
| 61 | Cole Hamels | .250 | 2007-2022 | |
| 64 | German Marquez# | .167 | 2018-2025 | |
| 64 | Matt Moore# | .167 | 2012-2025 | |
| 66 | Chad Bettis | .000 | 2012-2019 | |
| 66 | Dylan Cease# | .000 | 2015-2025 | |
| 66 | Jaime Garcia | .000 | 2011-2017 | |
| 66 | Freddy Peralta# | .000 | 2019-2025 |
