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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | GS | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Justin Verlander# | 20 | 2007-2025 | |
| 2 | Aaron Nola# | 19 | 2015-2025 | |
| 3 | David Price | 17 | 2009-2023 | |
| 4 | Catfish Hunter | 15 | 1965-1976 | |
| 5 | Clayton Kershaw# | 14 | 2009-2025 | |
| 5 | Max Scherzer# | 14 | 2009-2025 | |
| 7 | Gerrit Cole# | 13 | 2012-2025 | |
| 7 | Zack Wheeler# | 13 | 2010-2025 | |
| 9 | Madison Bumgarner | 11 | 2011-2023 | |
| 9 | Corbin Burnes# | 11 | 2020-2025 | |
| 9 | Carlos Carrasco | 11 | 2010-2023 | |
| 9 | Jacob Degrom# | 11 | 2012-2025 | |
| 9 | Lance McCullers Jr.# | 11 | 2016-2025 | |
| 9 | Jake Odorizzi | 11 | 2012-2023 | |
| 9 | Shohei Ohtani# | 11 | 2018-2025 | |
| 16 | Marcus Stroman# | 10 | 2015-2024 | |
| 16 | Adam Wainwright | 10 | 2004-2023 | |
| 18 | Walker Buehler# | 9 | 2019-2025 | |
| 18 | Pablo Lopez# | 9 | 2021-2025 | |
| 18 | Tyler Mahle# | 9 | 2017-2025 | |
| 18 | Miles Mikolas# | 9 | 2010-2025 | |
| 22 | Johnny Cueto | 8 | 2010-2023 | |
| 22 | Corey Kluber | 8 | 2011-2023 | |
| 22 | Robbie Ray# | 8 | 2017-2025 | |
| 22 | Carlos Rodon# | 8 | 2015-2025 | |
| 22 | Blake Snell# | 8 | 2012-2025 | |
| 27 | Matthew Boyd# | 7 | 2019-2025 | |
| 27 | Yu Darvish# | 7 | 2012-2025 | |
| 27 | Jeurys Familia | 7 | 2010-2022 | |
| 27 | Sandy Koufax | 7 | 1955-1966 | |
| 27 | German Marquez# | 7 | 2018-2025 | |
| 27 | Freddy Peralta# | 7 | 2019-2025 | |
| 27 | Jose Quintana# | 7 | 2013-2025 | |
| 27 | Stephen Strasburg# | 7 | 2010-2025 | |
| 27 | Julio Urias# | 7 | 2018-2023 | |
| 27 | Edinson Volquez | 7 | 2008-2020 | |
| 37 | Chris Archer | 6 | 2012-2023 | |
| 37 | Trevor Bauer | 6 | 2012-2023 | |
| 37 | Chad Bettis | 6 | 2012-2019 | |
| 37 | Dylan Cease# | 6 | 2015-2025 | |
| 37 | Zachary Davies | 6 | 2012-2023 | |
| 37 | Nathan Eovaldi# | 6 | 2012-2025 | |
| 37 | Kevin Gausman# | 6 | 2013-2025 | |
| 37 | Cole Hamels | 6 | 2007-2022 | |
| 37 | Derek Holland | 6 | 2010-2019 | |
| 37 | Shane McClanahan# | 6 | 2023-2025 | |
| 37 | Ryan Pressley | 6 | 2010-2012 | |
| 37 | Chris Sale# | 6 | 2011-2024 | |
| 49 | Sandy Alcantara# | 5 | 2018-2025 | |
| 49 | John Danks | 5 | 2008-2018 | |
| 49 | Gio Gonzalez | 5 | 2010-2022 | |
| 49 | Matt Harvey | 5 | 2014-2021 | |
| 49 | Kyle Hendricks# | 5 | 2016-2024 | |
| 49 | Merrill Kelly# | 5 | 2019-2024 | |
| 49 | Jon Lester | 5 | 2007-2021 | |
| 49 | Charlie Morton# | 5 | 2010-2025 | |
| 49 | Chris Paddack# | 5 | 2020-2025 | |
| 49 | Michael Pineda | 5 | 2011-2023 | |
| 49 | Trevor Richards# | 5 | 2019-2022 | |
| 49 | Hyun-Jin Ryu | 5 | 2013-2023 | |
| 49 | Kodai Senga# | 5 | 2023-2025 | |
| 49 | James Shields | 5 | 2007-2019 | |
| 49 | Smith Smith | 5 | 2006-2020 | |
| 49 | Smith Smith | 5 | 2004-2017 | |
| 49 | Justin Steele# | 5 | 2015-2025 | |
| 66 | Homer Bailey | 4 | 2009-2020 | |
| 66 | Miguel Celestino | 4 | 2012-2012 | |
| 66 | Wei-Yin Chen | 4 | 2012-2018 | |
| 66 | Tim Crabbe | 4 | 2010-2012 | |
| 66 | Erik Davis | 4 | 2010-2015 | |
| 66 | Wade Davis | 4 | 2009-2020 | |
| 66 | Ross Detwiler | 4 | 2011-2023 | |
| 66 | Zach Eflin# | 4 | 2018-2025 | |
| 66 | Kendry Flores | 4 | 2016-2021 | |
| 66 | Christian Friedrich | 4 | 2010-2022 | |
| 66 | Jaime Garcia | 4 | 2011-2017 | |
| 66 | Jon Gray# | 4 | 2015-2025 | |
| 66 | Vladimir Gutierrez# | 4 | 2022-2024 | |
| 66 | Ryan Helsley# | 4 | 2020-2025 | |
| 66 | Edgar Ibarra | 4 | 2010-2011 | |
| 66 | Chris Jones | 4 | 2010-2012 | |
| 66 | Mat Latos | 4 | 2010-2016 | |
| 66 | Nick Martinez# | 4 | 2012-2024 | |
| 66 | Matt Moore# | 4 | 2012-2025 | |
| 66 | Jon Niese | 4 | 2009-2016 | |
| 66 | Luis Patino# | 4 | 2022-2023 | |
| 66 | James Paxton# | 4 | 2014-2024 | |
| 66 | Adys Portillo | 4 | 2010-2012 | |
| 66 | Jose Junior Rosario | 4 | 2012-2017 | |
| 66 | Patrick Sandoval# | 4 | 2021-2025 | |
| 66 | Luis Severino# | 4 | 2016-2025 | |
| 66 | Tarik Skubal# | 4 | 2022-2025 | |
| 66 | Justin Souza | 4 | 2012-2012 | |
| 66 | Matt Swynenberg | 4 | 2010-2012 | |
| 66 | Bryse Wilson# | 4 | 2020-2025 | |
| 96 | Jeff Ames | 3 | 2012-2012 | |
| 96 | Tyler Anderson# | 3 | 2012-2025 | |
| 96 | Shawn Armstrong# | 3 | 2012-2025 | |
| 96 | Scott Baker | 3 | 2006-2014 | |
| 96 | Lisalberto Bonilla | 3 | 2012-2012 |
