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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | H | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Aaron Nola# | 110 | 2015-2025 | |
| 2 | David Price | 97 | 2009-2023 | |
| 3 | Justin Verlander# | 94 | 2007-2025 | |
| 4 | Catfish Hunter | 88 | 1965-1976 | |
| 5 | Clayton Kershaw# | 79 | 2009-2025 | |
| 6 | Gerrit Cole# | 72 | 2012-2025 | |
| 7 | Max Scherzer# | 71 | 2009-2025 | |
| 8 | Adam Wainwright | 65 | 2004-2023 | |
| 9 | Marcus Stroman# | 63 | 2015-2024 | |
| 10 | Miles Mikolas# | 62 | 2010-2025 | |
| 11 | Zack Wheeler# | 60 | 2010-2025 | |
| 12 | Carlos Carrasco | 59 | 2010-2023 | |
| 12 | Corey Kluber | 59 | 2011-2023 | |
| 14 | Madison Bumgarner | 57 | 2011-2023 | |
| 15 | Carlos Rodon# | 56 | 2015-2025 | |
| 16 | Walker Buehler# | 54 | 2019-2025 | |
| 16 | Tyler Mahle# | 54 | 2017-2025 | |
| 18 | Shohei Ohtani# | 52 | 2018-2025 | |
| 19 | Johnny Cueto | 48 | 2010-2023 | |
| 19 | Wade Davis | 48 | 2009-2020 | |
| 19 | Jacob Degrom# | 48 | 2012-2025 | |
| 19 | Pablo Lopez# | 48 | 2021-2025 | |
| 23 | Lance McCullers Jr.# | 47 | 2016-2025 | |
| 23 | Jake Odorizzi | 47 | 2012-2023 | |
| 25 | German Marquez# | 46 | 2018-2025 | |
| 26 | Corbin Burnes# | 43 | 2020-2025 | |
| 26 | Jeurys Familia | 43 | 2010-2022 | |
| 26 | Julio Urias# | 43 | 2018-2023 | |
| 29 | Jose Quintana# | 42 | 2013-2025 | |
| 30 | Jaime Garcia | 41 | 2011-2017 | |
| 30 | Robbie Ray# | 41 | 2017-2025 | |
| 32 | Yu Darvish# | 39 | 2012-2025 | |
| 32 | James Shields | 39 | 2007-2019 | |
| 32 | Logan Webb# | 39 | 2015-2025 | |
| 35 | Matthew Boyd# | 38 | 2019-2025 | |
| 36 | Hyun-Jin Ryu | 37 | 2013-2023 | |
| 36 | Smith Smith | 37 | 2004-2017 | |
| 36 | Edinson Volquez | 37 | 2008-2020 | |
| 39 | Sandy Koufax | 36 | 1955-1966 | |
| 39 | Chris Sale# | 36 | 2011-2024 | |
| 39 | Smith Smith | 36 | 2006-2020 | |
| 42 | Kevin Gausman# | 35 | 2013-2025 | |
| 42 | Blake Snell# | 35 | 2012-2025 | |
| 42 | Stephen Strasburg# | 35 | 2010-2025 | |
| 45 | John Danks | 34 | 2008-2018 | |
| 45 | Zach Eflin# | 34 | 2018-2025 | |
| 47 | Sandy Alcantara# | 33 | 2018-2025 | |
| 47 | Chad Bettis | 33 | 2012-2019 | |
| 47 | Matt Moore# | 33 | 2012-2025 | |
| 50 | Gio Gonzalez | 32 | 2010-2022 | |
| 50 | Jon Lester | 32 | 2007-2021 | |
| 52 | Chris Archer | 31 | 2012-2023 | |
| 52 | Nathan Eovaldi# | 31 | 2012-2025 | |
| 52 | Ryan Pressley | 31 | 2010-2012 | |
| 52 | Jose Junior Rosario | 31 | 2012-2017 | |
| 56 | Dylan Cease# | 30 | 2015-2025 | |
| 56 | Ross Detwiler | 30 | 2011-2023 | |
| 56 | Wade Miley# | 30 | 2010-2024 | |
| 56 | Charlie Morton# | 30 | 2010-2025 | |
| 56 | Trevor Richards# | 30 | 2019-2022 | |
| 61 | Wei-Yin Chen | 29 | 2012-2018 | |
| 61 | Shelby Miller# | 29 | 2012-2023 | |
| 63 | Trevor Bauer | 28 | 2012-2023 | |
| 63 | Derek Holland | 28 | 2010-2019 | |
| 65 | Homer Bailey | 27 | 2009-2020 | |
| 65 | Scott Baker | 27 | 2006-2014 | |
| 65 | Jon Gray# | 27 | 2015-2025 | |
| 65 | Matt Harvey | 27 | 2014-2021 | |
| 65 | Freddy Peralta# | 27 | 2019-2025 | |
| 70 | Vladimir Gutierrez# | 26 | 2022-2024 | |
| 70 | Cole Hamels | 26 | 2007-2022 | |
| 70 | Ryan Helsley# | 26 | 2020-2025 | |
| 70 | Hisashi Iwakuma | 26 | 2013-2018 | |
| 70 | Shane McClanahan# | 26 | 2023-2025 | |
| 70 | Chris Paddack# | 26 | 2020-2025 | |
| 70 | Michael Pineda | 26 | 2011-2023 | |
| 77 | Dellin Betances | 25 | 2011-2021 | |
| 77 | Ryan Brasier# | 25 | 2010-2025 | |
| 77 | Nick Pivetta# | 25 | 2019-2025 | |
| 77 | Bryse Wilson# | 25 | 2020-2025 | |
| 81 | Zachary Davies | 24 | 2012-2023 | |
| 81 | Kenley Jansen# | 24 | 2012-2025 | |
| 81 | Merrill Kelly# | 24 | 2019-2024 | |
| 81 | Craig Kimbrel# | 24 | 2011-2025 | |
| 81 | Cory Luebke | 24 | 2011-2015 | |
| 86 | Justin Steele# | 23 | 2015-2025 | |
| 87 | Jeff Ames | 22 | 2012-2012 | |
| 87 | Tyler Anderson# | 22 | 2012-2025 | |
| 87 | Jose Berrios# | 22 | 2016-2025 | |
| 87 | Christian Friedrich | 22 | 2010-2022 | |
| 87 | Mat Latos | 22 | 2010-2016 | |
| 87 | Taylor Rogers# | 22 | 2018-2025 | |
| 93 | Jose Alvarez | 21 | 2010-2023 | |
| 93 | Joe Gunkel | 21 | 2020-2021 | |
| 93 | Andrew Kittredge# | 21 | 2019-2025 | |
| 93 | Carlos Martinez | 21 | 2016-2022 | |
| 93 | Jeff Samardzija | 21 | 2010-2020 | |
| 93 | Chris Tillman | 21 | 2010-2020 | |
| 99 | Shawn Armstrong# | 20 | 2012-2025 | |
| 99 | Matt Cain | 20 | 2006-2019 |
