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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | OSLG | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Chris Jones | .1650 | 2010-2012 | |
| 2 | Kyle Hendricks# | .2000 | 2016-2024 | |
| 3 | Sandy Koufax | .2090 | 1955-1966 | |
| 4 | Justin Souza | .2478 | 2012-2012 | |
| 5 | Jacob Degrom# | .2760 | 2012-2025 | |
| 6 | Craig Kimbrel# | .2868 | 2011-2025 | |
| 7 | Shane McClanahan# | .2880 | 2023-2025 | |
| 8 | Mat Latos | .2957 | 2010-2016 | |
| 9 | Yu Darvish# | .2959 | 2012-2025 | |
| 10 | Cole Hamels | .3017 | 2007-2022 | |
| 11 | Jon Niese | .3019 | 2009-2016 | |
| 12 | Gio Gonzalez | .3023 | 2010-2022 | |
| 13 | Stephen Strasburg# | .3099 | 2010-2025 | |
| 14 | Dellin Betances | .3106 | 2011-2021 | |
| 15 | Tarik Skubal# | .3115 | 2022-2025 | |
| 16 | Jeurys Familia | .3118 | 2010-2022 | |
| 17 | Catfish Hunter | .3151 | 1965-1976 | |
| 18 | Lance McCullers Jr.# | .3223 | 2016-2025 | |
| 19 | Madison Bumgarner | .3234 | 2011-2023 | |
| 20 | Gerrit Cole# | .3246 | 2012-2025 | |
| 21 | Chris Archer | .3264 | 2012-2023 | |
| 22 | Carlos Carrasco | .3347 | 2010-2023 | |
| 23 | Trevor Bauer | .3419 | 2012-2023 | |
| 24 | Blake Snell# | .3503 | 2012-2025 | |
| 25 | Corbin Burnes# | .3522 | 2020-2025 | |
| 26 | Merrill Kelly# | .3529 | 2019-2025 | |
| 27 | Nathan Eovaldi# | .3551 | 2012-2025 | |
| 28 | Michael Pineda | .3583 | 2011-2023 | |
| 29 | Justin Verlander# | .3671 | 2007-2025 | |
| 30 | Jose Quintana# | .3735 | 2013-2025 | |
| 31 | Aaron Nola# | .3842 | 2015-2025 | |
| 32 | Homer Bailey | .3884 | 2009-2020 | |
| 33 | Charlie Morton# | .3889 | 2010-2025 | |
| 34 | Derek Holland | .3893 | 2010-2019 | |
| 35 | Max Scherzer# | .3975 | 2009-2025 | |
| 36 | Adam Wainwright | .4000 | 2004-2023 | |
| 37 | Shohei Ohtani# | .4009 | 2018-2025 | |
| 38 | German Marquez# | .4011 | 2018-2025 | |
| 39 | Wade Davis | .4043 | 2009-2020 | |
| 40 | Chad Bettis | .4094 | 2012-2019 | |
| 41 | Zack Wheeler# | .4122 | 2010-2025 | |
| 42 | Tyler Mahle# | .4135 | 2017-2025 | |
| 43 | Jaime Garcia | .4186 | 2011-2017 | |
| 44 | Edinson Volquez | .4211 | 2008-2020 | |
| 45 | Walker Buehler# | .4241 | 2019-2025 | |
| 46 | Smith Smith | .4245 | 2004-2017 | |
| 47 | Ryan Pressley | .4252 | 2010-2012 | |
| 48 | Corey Kluber | .4258 | 2011-2023 | |
| 49 | Jake Odorizzi | .4279 | 2012-2023 | |
| 50 | David Price | .4360 | 2009-2023 | |
| 51 | Dylan Cease# | .4370 | 2015-2025 | |
| 52 | Johnny Cueto | .4385 | 2010-2023 | |
| 53 | Matt Moore# | .4400 | 2012-2025 | |
| 54 | Clayton Kershaw# | .4430 | 2009-2025 | |
| 55 | Marcus Stroman# | .4631 | 2015-2025 | |
| 56 | Freddy Peralta# | .4640 | 2019-2025 | |
| 57 | Ross Detwiler | .4649 | 2011-2023 | |
| 58 | Carlos Rodon# | .4660 | 2015-2025 | |
| 59 | Miles Mikolas# | .5000 | 2010-2025 | |
| 60 | Logan Webb# | .5083 | 2015-2025 | |
| 61 | Pablo Lopez# | .5155 | 2021-2025 | |
| 62 | Hyun-Jin Ryu | .5177 | 2013-2023 | |
| 63 | Julio Urias# | .5227 | 2018-2025 | |
| 64 | Matthew Boyd# | .5360 | 2019-2025 |
