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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Chris O'Brien | 2012-2012 | .173 | 1 | 4 | 0 | 0 | 0 | 0.00 | 0 |
| Mikey O'Brien | 2010-2012 | .000 | 0 | 0 | 1 | 3 | 1 | 3.08 | 13 |
| Riley O'Brien | 2022-2022 | .000 | 0 | 0 | 0 | 0 | 0 | 10.29 | 3 |
| Colin O'Connell | 2012-2012 | .000 | 0 | 0 | 0 | 0 | 0 | 5.68 | 6 |
| Justin O'Conner | 2012-2012 | .155 | 0 | 8 | 0 | 0 | 0 | 0.00 | 0 |
| Darren O'Day | 2010-2022 | .000 | 0 | 0 | 40 | 33 | 92 | 3.78 | 851 |
| Billy O'Dell | 1954-1967 | .125 | 2 | 19 | 105 | 100 | 48 | 3.29 | 1133 |
| Eric O'Flaherty | 2007-2016 | .000 | 0 | 0 | 18 | 24 | 40 | 3.94 | 563 |
| Brian O'Grady | 2015-2020 | .125 | 0 | 3 | 4 | 9 | 0 | 6.67 | 74 |
| Ryan O'Hearn | 2015-2022 | .236 | 27 | 79 | 4 | 2 | 0 | 2.49 | 103 |
| Brian O'Keefe | 2015-2015 | .000 | 0 | 0 | 5 | 8 | 0 | 6.03 | 85 |
| Shawn O'Malley | 2010-2011 | .216 | 0 | 45 | 0 | 0 | 0 | 0.00 | 0 |
| Mike O'Neill | 2012-2014 | .333 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Tyler O'Neill | 2018-2023 | .282 | 91 | 267 | 0 | 0 | 0 | 0.00 | 0 |
| Ryan O'Sullivan | 2012-2012 | .000 | 0 | 0 | 1 | 3 | 0 | 2.60 | 20 |
| Sean O'Sullivan | 2011-2011 | .000 | 0 | 0 | 0 | 1 | 0 | 12.00 | 5 |
| Trevor Oaks | 2015-2019 | .257 | 1 | 35 | 12 | 19 | 0 | 5.57 | 184 |
| Bailey Ober | 2022-2023 | .000 | 0 | 0 | 6 | 15 | 1 | 4.65 | 158 |
| Chad Oberacker | 2012-2012 | .083 | 0 | 3 | 0 | 0 | 0 | 0.00 | 0 |
| Scott Oberg | 2019-2022 | .000 | 0 | 0 | 15 | 14 | 38 | 2.95 | 229 |
| Brett Oberholtzer | 2010-2016 | .143 | 0 | 1 | 13 | 9 | 0 | 3.89 | 160 |
| Josh Ockimey | 2015-2015 | .381 | 0 | 11 | 8 | 3 | 0 | 2.91 | 85 |
| Rougned Odor | 2012-2023 | .243 | 103 | 348 | 0 | 0 | 0 | 0.00 | 0 |
| Jake Odorizzi | 2012-2023 | .136 | 0 | 24 | 85 | 64 | 1 | 4.27 | 1160 |
| Alexi Ogando | 2012-2017 | .182 | 0 | 0 | 27 | 32 | 36 | 4.09 | 407 |
| Cesar Ogando | 2012-2012 | .000 | 0 | 0 | 3 | 5 | 0 | 1.66 | 27 |
| Emilio Ogando | 2015-2015 | .259 | 5 | 37 | 0 | 0 | 0 | 0.00 | 0 |
| Nefi Ogando | 2017-2017 | .000 | 0 | 0 | 1 | 2 | 0 | 4.26 | 35 |
| Seung-hwan Oh | 2016-2019 | .333 | 0 | 0 | 5 | 11 | 9 | 4.03 | 267 |
| Ross Ohlendorf | 2009-2011 | .286 | 0 | 3 | 11 | 15 | 3 | 5.46 | 175 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Michael Ohlman | 2010-2017 | .208 | 5 | 41 | 0 | 0 | 0 | 0.00 | 0 |
| Shohei Ohtani | 2018-2023 | .267 | 119 | 338 | 66 | 37 | 0 | 4.03 | 952 |
| Gabriel Ojeda | 2015-2015 | .000 | 0 | 0 | 3 | 6 | 0 | 5.75 | 79 |
| Steven Okert | 2016-2023 | .000 | 0 | 0 | 8 | 5 | 1 | 4.08 | 171 |
| Jared Oliva | 2021-2021 | .154 | 1 | 1 | 0 | 0 | 0 | 0.00 | 0 |
| Edward Olivares | 2022-2023 | .238 | 6 | 34 | 0 | 0 | 0 | 0.00 | 0 |
| Andy Oliver | 2010-2012 | .000 | 0 | 0 | 3 | 1 | 6 | 2.54 | 26 |
| Hector Olivera | 2015-2017 | .249 | 23 | 89 | 0 | 0 | 0 | 0.00 | 0 |
| Lester Oliveros | 2016-2016 | .333 | 0 | 0 | 7 | 6 | 4 | 4.84 | 98 |
| Manny Olloque | 2015-2015 | .000 | 0 | 0 | 4 | 7 | 0 | 6.19 | 78 |
| Alexis Olmeda | 2019-2019 | .151 | 1 | 2 | 0 | 0 | 0 | 0.00 | 0 |
| Edgar Olmos | 2010-2015 | .500 | 0 | 0 | 0 | 6 | 2 | 6.20 | 55 |
| Matt Olson | 2017-2023 | .255 | 207 | 555 | 0 | 0 | 0 | 0.00 | 0 |
| Tyler Olson | 2018-2019 | .000 | 0 | 0 | 4 | 1 | 4 | 4.86 | 65 |
| Mike Olt | 2012-2016 | .188 | 9 | 37 | 0 | 0 | 0 | 0.00 | 0 |
| Logan Ondrusek | 2012-2016 | .200 | 0 | 0 | 6 | 8 | 3 | 3.69 | 128 |
| Jonathan Oquendo | 2015-2015 | .402 | 2 | 29 | 0 | 0 | 0 | 0.00 | 0 |
| Magglio Ordonez Jr. | 2015-2015 | .000 | 0 | 0 | 6 | 9 | 0 | 7.03 | 58 |
| Paulo Orlando | 2010-2017 | .266 | 27 | 145 | 0 | 0 | 0 | 0.00 | 0 |
| Ricky Oropesa | 2012-2012 | .147 | 1 | 6 | 0 | 0 | 0 | 0.00 | 0 |
| Jose Ortega | 2012-2012 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Rafael Ortega | 2012-2023 | .253 | 17 | 90 | 0 | 0 | 0 | 0.00 | 0 |
| Danny Ortiz | 2010-2012 | .211 | 9 | 58 | 0 | 0 | 0 | 0.00 | 0 |
| Joey Ortiz | 2023-2023 | .272 | 2 | 26 | 0 | 0 | 0 | 0.00 | 0 |
| Joseph Ortiz | 2010-2014 | .000 | 0 | 0 | 6 | 4 | 2 | 4.35 | 122 |
| Luis Ortiz | 2023-2023 | .000 | 0 | 0 | 2 | 3 | 0 | 4.80 | 38 |
| Luis Ortiz | 2015-2015 | .259 | 4 | 53 | 0 | 0 | 0 | 0.00 | 0 |
| Ryan Ortiz | 2010-2012 | .230 | 4 | 63 | 0 | 0 | 0 | 0.00 | 0 |
| Josh Osich | 2012-2019 | .000 | 0 | 0 | 9 | 2 | 4 | 2.96 | 92 |
| Jose Osuna | 2012-2020 | .228 | 6 | 35 | 0 | 0 | 0 | 27.00 | 1 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Ramon Osuna | 2017-2017 | .268 | 17 | 55 | 0 | 0 | 0 | 0.00 | 0 |
| Roberto Osuna | 2016-2022 | .000 | 0 | 1 | 33 | 35 | 139 | 3.32 | 459 |
| Corey Oswalt | 2018-2018 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Andy Otero | 2012-2012 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Dan Otero | 2010-2019 | .000 | 0 | 0 | 27 | 16 | 22 | 3.43 | 406 |
| Sharif Othman | 2012-2012 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Mel Ott | 1947-1947 | .000 | 0 | 0 | 0 | 0 | 0 | 0.00 | 0 |
| Travis Ott | 2018-2020 | .000 | 0 | 0 | 4 | 1 | 0 | 4.55 | 65 |
| Adam Ottavino | 2010-2023 | .067 | 1 | 4 | 44 | 35 | 40 | 4.13 | 878 |
| Glenn Otto | 2022-2023 | .000 | 0 | 0 | 1 | 3 | 0 | 5.40 | 32 |
| Connor Overton | 2015-2015 | .000 | 0 | 0 | 4 | 8 | 0 | 6.08 | 87 |
| Dillon Overton | 2017-2017 | .080 | 0 | 0 | 3 | 4 | 0 | 3.69 | 63 |
| Johan Oviedo | 2022-2022 | .000 | 0 | 0 | 3 | 2 | 0 | 2.59 | 53 |
| Juan Oviedo | 2008-2014 | .000 | 0 | 0 | 19 | 15 | 18 | 4.23 | 318 |
| Henry Owens | 2012-2012 | .000 | 0 | 0 | 1 | 1 | 0 | 2.21 | 20 |
| Rudy Owens | 2010-2016 | .123 | 0 | 4 | 11 | 23 | 4 | 5.17 | 263 |
| Chris Owings | 2010-2019 | .244 | 38 | 190 | 0 | 0 | 0 | 0.00 | 0 |
| Marcell Ozuna | 2012-2023 | .257 | 199 | 615 | 0 | 0 | 0 | 0.00 | 0 |
