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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
|---|---|---|---|---|---|---|---|---|---|
| Chris O'Brien | 2015-2015 | .230 | 2 | 12 | 0 | 0 | 0 | 0.00 | 0 |
| Riley O'Brien | 2020-2020 | .000 | 0 | 0 | 5 | 9 | 2 | 6.25 | 86 |
| Justin O'Conner | 2016-2018 | .246 | 15 | 67 | 0 | 0 | 0 | 0.00 | 0 |
| Chris O'Grady | 2017-2021 | .000 | 0 | 0 | 12 | 19 | 0 | 4.91 | 198 |
| Logan O'Hoppe | 2023-2023 | .339 | 26 | 81 | 0 | 0 | 0 | 0.00 | 0 |
| Brian O'Keefe | 2020-2023 | .258 | 14 | 68 | 0 | 0 | 0 | 0.00 | 0 |
| Shawn O'Malley | 2016-2017 | .268 | 6 | 84 | 0 | 0 | 0 | 0.00 | 0 |
| Tyler O'Neill | 2018-2019 | .336 | 44 | 138 | 0 | 0 | 0 | 0.00 | 0 |
| Sean O'Sullivan | 2015-2018 | .000 | 0 | 0 | 12 | 15 | 0 | 5.38 | 161 |
| Trevor Oaks | 2019-2021 | .000 | 0 | 0 | 6 | 3 | 6 | 6.53 | 50 |
| Bailey Ober | 2023-2023 | .000 | 0 | 0 | 2 | 1 | 0 | 1.86 | 17 |
| Chad Oberacker | 2015-2016 | .238 | 5 | 20 | 0 | 0 | 0 | 0.00 | 0 |
| Scott Oberg | 2023-2023 | .000 | 0 | 0 | 0 | 1 | 0 | 1.12 | 6 |
| Brett Oberholtzer | 2013-2021 | .000 | 0 | 0 | 47 | 48 | 9 | 4.52 | 645 |
| Matthew Oberste | 2017-2017 | .300 | 11 | 54 | 0 | 0 | 0 | 0.00 | 0 |
| Wilmer Oberto | 2015-2015 | .197 | 3 | 16 | 0 | 0 | 0 | 0.00 | 0 |
| Josh Ockimey | 2021-2022 | .251 | 38 | 106 | 0 | 0 | 0 | 0.00 | 0 |
| Jake Odorizzi | 2013-2014 | .000 | 0 | 0 | 19 | 17 | 0 | 4.91 | 218 |
| Alexi Ogando | 2013-2013 | .000 | 0 | 0 | 6 | 3 | 0 | 3.11 | 52 |
| Nefi Ogando | 2017-2018 | .000 | 0 | 0 | 0 | 1 | 9 | 3.06 | 39 |
| Tyler Ogle | 2016-2016 | .232 | 1 | 14 | 0 | 0 | 0 | 0.00 | 0 |
| Seung-hwan Oh | 2018-2020 | .000 | 0 | 0 | 5 | 5 | 26 | 3.19 | 83 |
| Ross Ohlendorf | 2013-2016 | .000 | 0 | 0 | 30 | 16 | 1 | 4.76 | 306 |
| Michael Ohlman | 2015-2019 | .282 | 58 | 226 | 0 | 0 | 0 | 0.00 | 0 |
| Shohei Ohtani | 2023-2023 | .371 | 4 | 9 | 0 | 0 | 0 | 0.73 | 15 |
| Steven Okert | 2018-2022 | .000 | 0 | 0 | 12 | 6 | 5 | 4.62 | 97 |
| Jon Olczak | 2019-2023 | .000 | 0 | 0 | 2 | 0 | 2 | 3.76 | 24 |
| Andy Oliver | 2016-2018 | .000 | 0 | 0 | 8 | 8 | 0 | 4.86 | 105 |
| Adam Oller | 2022-2022 | .000 | 0 | 0 | 5 | 4 | 5 | 6.39 | 45 |
| Manny Olloque | 2020-2020 | .282 | 6 | 43 | 0 | 0 | 0 | 0.00 | 0 |
| Player | From-To | Avg | HR | RBI | W | L | SV | ERA | K |
| Edgar Olmos | 2014-2015 | .000 | 0 | 0 | 0 | 3 | 2 | 5.46 | 49 |
| Matt Olson | 2018-2019 | .330 | 43 | 150 | 0 | 0 | 0 | 0.00 | 0 |
| Mike Olt | 2016-2016 | .261 | 16 | 41 | 0 | 0 | 0 | 0.00 | 0 |
| Jorge Ona | 2021-2022 | .280 | 32 | 88 | 0 | 0 | 0 | 0.00 | 0 |
| Shane Opitz | 2015-2016 | .247 | 9 | 60 | 0 | 0 | 0 | 0.00 | 0 |
| Nathan Orf | 2018-2021 | .263 | 34 | 154 | 0 | 0 | 0 | 6.75 | 3 |
| Paulo Orlando | 2014-2020 | .320 | 44 | 216 | 0 | 0 | 0 | 0.00 | 0 |
| Ricky Oropesa | 2014-2016 | .284 | 27 | 107 | 0 | 0 | 0 | 0.00 | 0 |
| Jose Ortega | 2014-2017 | .000 | 0 | 0 | 9 | 12 | 14 | 4.91 | 250 |
| Rafael Ortega | 2015-2021 | .281 | 37 | 180 | 0 | 0 | 0 | 0.00 | 0 |
| Jesus Ortiz | 2018-2018 | .000 | 0 | 0 | 1 | 4 | 0 | 9.07 | 37 |
| Joey Ortiz | 2023-2023 | .286 | 6 | 9 | 0 | 0 | 0 | 0.00 | 0 |
| Joseph Ortiz | 2013-2016 | .000 | 0 | 0 | 5 | 2 | 0 | 2.40 | 53 |
| Luis Ortiz | 2021-2023 | .000 | 0 | 0 | 6 | 4 | 2 | 4.64 | 81 |
| Eric Orze | 2022-2022 | .000 | 0 | 0 | 4 | 3 | 1 | 5.17 | 64 |
| Josh Osich | 2015-2018 | .000 | 0 | 0 | 7 | 10 | 0 | 7.12 | 171 |
| Jose Osuna | 2018-2021 | .329 | 73 | 336 | 0 | 0 | 0 | 0.00 | 0 |
| Roberto Osuna | 2015-2016 | .000 | 0 | 0 | 0 | 0 | 0 | 7.15 | 15 |
| Corey Oswalt | 2018-2023 | .000 | 0 | 0 | 24 | 28 | 1 | 5.95 | 299 |
| Dan Otero | 2017-2020 | .000 | 0 | 0 | 3 | 3 | 3 | 3.84 | 31 |
| Travis Ott | 2019-2020 | .000 | 0 | 0 | 0 | 1 | 2 | 3.86 | 5 |
| Adam Ottavino | 2013-2022 | .000 | 0 | 0 | 5 | 6 | 23 | 3.74 | 100 |
| James Outman | 2022-2023 | .260 | 11 | 28 | 0 | 0 | 0 | 0.00 | 0 |
| Johan Oviedo | 2021-2023 | .000 | 0 | 0 | 24 | 26 | 0 | 4.65 | 309 |
| Juan Oviedo | 2015-2015 | .000 | 0 | 0 | 2 | 0 | 1 | 5.08 | 29 |
| Henry Owens | 2014-2015 | .000 | 0 | 0 | 2 | 2 | 0 | 6.34 | 32 |
| Chris Owings | 2015-2019 | .320 | 7 | 21 | 0 | 0 | 0 | 0.00 | 0 |
| Ian Oxnevad | 2022-2022 | .000 | 0 | 0 | 4 | 11 | 15 | 5.87 | 75 |
| Marcell Ozuna | 2023-2023 | .500 | 4 | 9 | 0 | 0 | 0 | 0.00 | 0 |
