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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Ibandel Isabel# | 111 | 2018-2022 | |
| 2 | Josh Lester# | 104 | 2019-2023 | |
| 3 | Jorge Bonifacio# | 101 | 2016-2023 | |
| 4 | Alexander Palma# | 91 | 2019-2023 | |
| 5 | Bobby Coyle | 90 | 2013-2016 | |
| 5 | Aderlin Rodriguez# | 90 | 2016-2022 | |
| 7 | Kelvin Gutierrez# | 89 | 2018-2023 | |
| 8 | Peter O'Brien | 83 | 2015-2018 | |
| 9 | Franklin Barreto# | 82 | 2016-2023 | |
| 9 | Ryan Cordell# | 82 | 2015-2022 | |
| 11 | Luken Baker# | 78 | 2016-2018 | |
| 11 | D.J. Peters# | 78 | 2018-2022 | |
| 13 | Michael Gettys# | 70 | 2019-2021 | |
| 14 | Connor Panas# | 69 | 2018-2021 | |
| 15 | Telmito Agustin# | 67 | 2018-2023 | |
| 16 | Christin Stewart# | 65 | 2017-2020 | |
| 17 | Clint Coulter# | 64 | 2017-2023 | |
| 18 | Vince Fernandez# | 62 | 2019-2023 | |
| 18 | D.J. Peterson# | 62 | 2015-2023 | |
| 20 | Lewin Diaz# | 60 | 2019-2023 | |
| 21 | Royce Bolinger | 59 | 2018-2021 | |
| 21 | Gorman Erickson | 59 | 2013-2015 | |
| 21 | Telvin Nash | 59 | 2015-2019 | |
| 24 | Ben Ruta# | 58 | 2017-2022 | |
| 25 | Jaylin Davis# | 57 | 2016-2021 | |
| 25 | Gavin LaValley | 57 | 2017-2021 | |
| 27 | Stetson Allie | 55 | 2017-2020 | |
| 27 | Mandy Alvarez# | 55 | 2019-2023 | |
| 27 | Daniel Butler | 55 | 2013-2017 | |
| 27 | Zach Walters | 55 | 2013-2018 | |
| 31 | Trey Amburgey# | 54 | 2016-2023 | |
| 31 | Dilson Herrera# | 54 | 2019-2022 | |
| 31 | Victor Roache | 54 | 2016-2019 | |
| 31 | Ramon Urias# | 54 | 2020-2021 | |
| 35 | Nick Evans | 52 | 2014-2016 | |
| 35 | Daniel Kihle | 52 | 2018-2021 | |
| 35 | Jordy Lara | 52 | 2018-2021 | |
| 38 | Michael Almanzar | 51 | 2014-2017 | |
| 38 | Zach Collier | 51 | 2014-2019 | |
| 38 | Tyler Marincov | 51 | 2017-2018 | |
| 41 | Joey Gallo# | 50 | 2014-2015 | |
| 41 | Jacoby Jones# | 50 | 2017-2022 | |
| 43 | Juan Diaz | 49 | 2014-2017 | |
| 43 | Eloy Jimenez# | 49 | 2018-2019 | |
| 43 | Dawel Lugo | 49 | 2016-2021 | |
| 46 | Jorge Alfaro# | 48 | 2014-2016 | |
| 46 | Brennen Davis# | 48 | 2021-2023 | |
| 46 | Fernando Tatis Jr.# | 48 | 2018-2019 | |
| 49 | Willi Castro# | 47 | 2018-2021 | |
| 49 | Hector Gomez | 47 | 2013-2017 | |
| 49 | Ernesto Mejia | 47 | 2013-2021 | |
| 49 | Ryan Schimpf | 47 | 2013-2016 | |
| 53 | Michael Busch# | 46 | 2021-2023 | |
| 53 | Lucas Erceg# | 46 | 2019-2023 | |
| 53 | Gilbert Gomez | 46 | 2014-2019 | |
| 53 | Jahmai Jones# | 46 | 2018-2021 | |
| 57 | Jose Herrera# | 45 | 2019-2023 | |
| 57 | Derek Hill# | 45 | 2020-2023 | |
| 57 | Connor Lien | 45 | 2016-2020 | |
| 57 | Kevin Smith# | 45 | 2019-2023 | |
| 57 | Brett Sullivan# | 45 | 2018-2023 | |
| 57 | Drew Vettleson | 45 | 2014-2019 | |
| 63 | Tres Barrera# | 44 | 2019-2023 | |
| 63 | Niko Goodrum# | 44 | 2014-2018 | |
| 63 | Nomar Mazara# | 44 | 2016-2022 | |
| 66 | Jodd Carter# | 43 | 2016-2022 | |
| 66 | Sherman Johnson | 43 | 2018-2022 | |
| 66 | Malcom Nunez# | 43 | 2022-2023 | |
| 66 | Henry Ramos# | 43 | 2015-2021 | |
| 70 | Sebastian Elizalde | 42 | 2015-2021 | |
| 70 | Zack Zehner | 42 | 2017-2022 | |
| 72 | B.J. Boyd# | 41 | 2017-2022 | |
| 72 | Kody Clemens# | 41 | 2019-2021 | |
| 72 | Cooper Hummel# | 41 | 2020-2023 | |
| 72 | Jake Scheiner# | 41 | 2020-2023 | |
| 72 | Jiandido Tromp | 41 | 2014-2019 | |
| 77 | Eliezer Alvarez | 40 | 2016-2022 | |
| 77 | Luis Barrera# | 40 | 2020-2023 | |
| 77 | Brett Eibner | 40 | 2013-2016 | |
| 77 | Dayron Varona | 40 | 2016-2018 | |
| 81 | Gabriel Guerrero# | 39 | 2015-2022 | |
| 81 | Chris Paul# | 39 | 2019-2022 | |
| 81 | Darwin Perez | 39 | 2013-2015 | |
| 81 | Taylor Walls# | 39 | 2020-2022 | |
| 85 | Kevin Cornelius | 38 | 2018-2019 | |
| 85 | Derek Dietrich | 38 | 2013-2015 | |
| 85 | Jim Haley# | 38 | 2019-2023 | |
| 85 | Patrick Leonard | 38 | 2014-2021 | |
| 85 | Richie Martin# | 38 | 2017-2023 | |
| 85 | Jared Young# | 38 | 2019-2023 | |
| 91 | Jacob Stallings# | 37 | 2013-2018 | |
| 92 | Luis Aviles# | 36 | 2019-2023 | |
| 92 | Skye Bolt# | 36 | 2018-2022 | |
| 92 | Yu Chang# | 36 | 2017-2020 | |
| 92 | Dom Nunez# | 36 | 2020-2021 | |
| 92 | Joe Odom | 36 | 2014-2022 | |
| 92 | Ronny Rodriguez# | 36 | 2013-2023 | |
| 92 | Tim Wheeler | 36 | 2014-2017 | |
| 99 | Nick Dini# | 35 | 2018-2022 | |
| 99 | Taylor Gushue# | 35 | 2020-2023 |
