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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | H | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | CC Sabathia | 3196 | 2002-2020 | |
| 2 | Smith Smith | 3114 | 2002-2017 | |
| 3 | Bartolo Colon | 2884 | 1997-2019 | |
| 4 | Adam Wainwright | 2837 | 2004-2023 | |
| 5 | John Lackey | 2596 | 2003-2017 | |
| 6 | Catfish Hunter | 2595 | 1965-1976 | |
| 7 | Justin Verlander# | 2559 | 2007-2025 | |
| 8 | Felix Hernandez | 2512 | 2005-2021 | |
| 9 | Smith Smith | 2477 | 2006-2020 | |
| 10 | Clayton Kershaw# | 2457 | 2009-2025 | |
| 11 | Aaron Harang | 2445 | 2002-2015 | |
| 12 | Cole Hamels | 2439 | 2007-2022 | |
| 13 | Jon Lester | 2360 | 2007-2021 | |
| 14 | Jake Peavy | 2353 | 2002-2018 | |
| 15 | J.J. Franco | 2345 | 1999-2014 | |
| 16 | Johnny Cueto | 2312 | 2010-2023 | |
| 17 | Lance Lynn# | 2211 | 2010-2025 | |
| 18 | Josh M. Johnson | 2204 | 2006-2017 | |
| 19 | Scott Kazmir | 2199 | 2005-2018 | |
| 20 | James Shields | 2193 | 2007-2019 | |
| 21 | Smith Smith | 2161 | 2004-2017 | |
| 22 | Brett Anderson | 2152 | 2010-2021 | |
| 23 | Jordan Zimmermann | 2097 | 2010-2021 | |
| 24 | Michael Pineda | 2095 | 2011-2023 | |
| 25 | Charlie Morton# | 2092 | 2010-2025 | |
| 26 | Larry Dierker | 2090 | 1964-1976 | |
| 27 | Matt Cain | 2086 | 2006-2019 | |
| 28 | Brandon McCarthy | 2070 | 2006-2019 | |
| 29 | Max Scherzer# | 2034 | 2009-2025 | |
| 30 | Zack Wheeler# | 2005 | 2010-2025 | |
| 31 | Anibal Sanchez | 1983 | 2007-2021 | |
| 32 | Jered Weaver | 1976 | 2007-2017 | |
| 33 | Brett Myers | 1969 | 2003-2014 | |
| 34 | Rich Hill# | 1965 | 2006-2023 | |
| 35 | David Price | 1913 | 2009-2023 | |
| 36 | Jake Arrieta | 1909 | 2011-2022 | |
| 37 | John Danks | 1890 | 2008-2018 | |
| 38 | Clay Buchholz | 1875 | 2008-2020 | |
| 39 | Johnny Antonelli | 1870 | 1948-1961 | |
| 39 | Jose Quintana# | 1870 | 2013-2025 | |
| 41 | Alex Cobb# | 1825 | 2012-2025 | |
| 42 | Ricky Nolasco | 1819 | 2007-2017 | |
| 43 | James Happ | 1815 | 2009-2022 | |
| 44 | Stephen Strasburg# | 1812 | 2010-2025 | |
| 45 | Madison Bumgarner | 1808 | 2011-2023 | |
| 46 | Kevin Gausman# | 1800 | 2013-2025 | |
| 47 | Bob Feller | 1795 | 1947-1956 | |
| 48 | Nathan Eovaldi# | 1788 | 2012-2025 | |
| 49 | Sandy Koufax | 1754 | 1955-1966 | |
| 50 | Gio Gonzalez | 1746 | 2010-2022 | |
| 51 | Ervin Santana | 1737 | 2002-2019 | |
| 52 | Chris Sale# | 1721 | 2011-2024 | |
| 52 | Edinson Volquez | 1721 | 2008-2020 | |
| 54 | Rick Porcello | 1711 | 2011-2021 | |
| 55 | Billy O'Dell | 1697 | 1954-1967 | |
| 56 | Gerrit Cole# | 1685 | 2012-2025 | |
| 57 | Michael Wacha# | 1667 | 2015-2025 | |
| 58 | Gavin Floyd | 1649 | 2005-2017 | |
| 59 | Wade Miley# | 1646 | 2010-2024 | |
| 60 | Julio Teheran | 1629 | 2011-2022 | |
| 61 | Jon Gray# | 1619 | 2015-2025 | |
| 62 | Jameson Taillon# | 1607 | 2014-2025 | |
| 63 | Paul Maholm | 1599 | 2006-2015 | |
| 64 | Chris Young | 1589 | 2004-2016 | |
| 65 | Joe Blanton | 1587 | 2006-2017 | |
| 66 | Kyle Gibson# | 1579 | 2010-2024 | |
| 67 | Kyle Hendricks# | 1571 | 2016-2024 | |
| 68 | Mike Minor | 1565 | 2010-2023 | |
| 69 | Homer Bailey | 1561 | 2009-2020 | |
| 70 | Jeff Samardzija | 1552 | 2010-2020 | |
| 71 | Ian Kennedy | 1547 | 2010-2022 | |
| 72 | Phil Hughes | 1540 | 2009-2018 | |
| 73 | Carlos Carrasco | 1531 | 2010-2023 | |
| 74 | Miles Mikolas# | 1524 | 2010-2025 | |
| 75 | Yu Darvish# | 1522 | 2012-2025 | |
| 76 | Hyun-Jin Ryu | 1521 | 2013-2023 | |
| 77 | Matt Moore# | 1504 | 2012-2025 | |
| 78 | Danny Duffy | 1499 | 2012-2022 | |
| 79 | Masahiro Tanaka | 1478 | 2014-2021 | |
| 80 | Jason Hammel | 1470 | 2008-2018 | |
| 81 | Garrett Richards | 1451 | 2012-2022 | |
| 82 | Dylan Bundy | 1448 | 2012-2023 | |
| 83 | Mike Leake | 1447 | 2010-2020 | |
| 84 | Josh Tomlin | 1439 | 2011-2022 | |
| 85 | Smith Smith | 1435 | 2008-2017 | |
| 86 | Jacob Degrom# | 1432 | 2012-2025 | |
| 87 | Tyler Mahle# | 1431 | 2017-2025 | |
| 88 | James Paxton# | 1429 | 2014-2024 | |
| 89 | Matt Garza | 1416 | 2009-2017 | |
| 89 | Corey Kluber | 1416 | 2011-2023 | |
| 91 | Ryan Madson | 1411 | 2003-2019 | |
| 91 | Ivan Nova | 1411 | 2011-2021 | |
| 93 | Derek Holland | 1406 | 2010-2019 | |
| 94 | Marcus Stroman# | 1393 | 2015-2024 | |
| 95 | Doug Fister | 1380 | 2011-2018 | |
| 96 | Chris Archer | 1378 | 2012-2023 | |
| 97 | Tyler Anderson# | 1377 | 2012-2025 | |
| 98 | Taijuan Walker# | 1352 | 2012-2025 | |
| 99 | Smith Smith | 1347 | 2005-2019 | |
| 100 | Sonny Gray# | 1341 | 2012-2025 |
