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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K9 | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Aroldis Chapman# | 13.72 | 2011-2025 | |
| 2 | Craig Kimbrel# | 13.37 | 2011-2025 | |
| 3 | Trevor Rosenthal | 12.15 | 2010-2023 | |
| 4 | Pedro Strop | 12.02 | 2011-2021 | |
| 5 | Tyler Clippard | 11.88 | 2007-2019 | |
| 6 | Joe Nathan | 11.74 | 2000-2016 | |
| 7 | Kenley Jansen# | 11.59 | 2012-2025 | |
| 8 | David Robertson# | 11.57 | 2010-2025 | |
| 9 | Shawn Kelley | 11.49 | 2010-2020 | |
| 9 | Jonathan Broxton | 11.49 | 2007-2017 | |
| 11 | Darren O'Day | 11.41 | 2010-2022 | |
| 11 | Sean Doolittle | 11.41 | 2011-2022 | |
| 13 | Francisco Rodriguez | 11.22 | 2003-2018 | |
| 14 | Steve Cishek | 10.88 | 2012-2021 | |
| 15 | Rafael Soriano | 10.84 | 2003-2015 | |
| 15 | Huston Street | 10.84 | 2005-2016 | |
| 17 | Jonathan Papelbon | 10.80 | 2006-2017 | |
| 18 | Evan Scribner | 10.79 | 2011-2018 | |
| 19 | Sergio Romo | 10.71 | 2010-2021 | |
| 20 | Koji Uehara | 10.54 | 2009-2018 | |
| 21 | Caleb Ferguson# | 10.51 | 2015-2025 | |
| 22 | Tim Lincecum | 10.47 | 2009-2018 | |
| 23 | Adam Ottavino# | 10.41 | 2010-2024 | |
| 24 | Tyler Glasnow# | 10.35 | 2017-2025 | |
| 25 | Smith Smith | 10.32 | 2005-2014 | |
| 26 | Matt Strahm# | 10.29 | 2016-2025 | |
| 27 | Smith Smith | 10.27 | 2002-2018 | |
| 28 | Fernando Rodney | 10.24 | 2005-2018 | |
| 29 | Luke Gregerson | 10.22 | 2010-2019 | |
| 30 | Jake McGee | 10.19 | 2010-2022 | |
| 30 | Yu Darvish# | 10.19 | 2012-2025 | |
| 32 | Brad Peacock | 10.18 | 2010-2021 | |
| 33 | Joakim Soria | 10.09 | 2007-2020 | |
| 34 | Oliver Perez | 10.07 | 2003-2022 | |
| 34 | Max Scherzer# | 10.07 | 2009-2025 | |
| 36 | Jason Grilli | 10.05 | 2001-2017 | |
| 37 | Raisel Iglesias# | 10.04 | 2016-2025 | |
| 37 | Robbie Ray# | 10.04 | 2017-2025 | |
| 39 | Jeurys Familia | 9.98 | 2010-2022 | |
| 39 | Hector Rondon | 9.98 | 2010-2021 | |
| 41 | Tanner Scheppers | 9.97 | 2010-2016 | |
| 42 | Freddy Peralta# | 9.94 | 2019-2025 | |
| 43 | Brandon Morrow | 9.90 | 2009-2020 | |
| 44 | Blake Snell# | 9.81 | 2012-2025 | |
| 45 | Juan Nicasio | 9.79 | 2010-2019 | |
| 46 | Trevor Bauer | 9.77 | 2012-2023 | |
| 47 | Mat Latos | 9.76 | 2010-2016 | |
| 48 | Tony Watson | 9.67 | 2011-2021 | |
| 48 | Jesse Crain | 9.67 | 2006-2015 | |
| 50 | Stephen Strasburg# | 9.66 | 2010-2025 | |
| 51 | Chris Sale# | 9.65 | 2011-2024 | |
| 52 | Smith Smith | 9.61 | 2006-2020 | |
| 53 | Clayton Kershaw# | 9.60 | 2009-2025 | |
| 54 | Andrew Miller | 9.58 | 2007-2020 | |
| 55 | Joel Peralta | 9.55 | 2005-2016 | |
| 56 | Santiago Casilla | 9.54 | 2005-2017 | |
| 57 | Jonathan Sanchez | 9.53 | 2009-2013 | |
| 58 | Jarrod Parker | 9.52 | 2012-2015 | |
| 59 | Liam Hendriks# | 9.51 | 2012-2025 | |
| 60 | Mark Melancon | 9.49 | 2010-2023 | |
| 61 | Shohei Ohtani# | 9.48 | 2018-2025 | |
| 62 | Drew Pomeranz | 9.45 | 2012-2023 | |
| 62 | Neal Cotts | 9.45 | 2005-2016 | |
| 64 | Gerrit Cole# | 9.42 | 2012-2025 | |
| 65 | Lance McCullers Jr.# | 9.41 | 2016-2025 | |
| 66 | Chris Archer | 9.34 | 2012-2023 | |
| 66 | Shelby Miller# | 9.34 | 2012-2023 | |
| 68 | Yusei Kikuchi# | 9.32 | 2019-2025 | |
| 69 | Kris Medlen | 9.30 | 2010-2016 | |
| 70 | Alex Colome | 9.28 | 2010-2022 | |
| 70 | Sandy Koufax | 9.28 | 1955-1966 | |
| 72 | Justin Verlander# | 9.24 | 2007-2025 | |
| 73 | J.P. Howell | 9.22 | 2008-2017 | |
| 74 | Neftali Feliz | 9.21 | 2010-2018 | |
| 74 | Carlos Villanueva | 9.21 | 2008-2016 | |
| 76 | Jake Peavy | 9.20 | 2002-2018 | |
| 77 | Jose De Leon# | 9.18 | 2017-2022 | |
| 78 | Lucas Giolito# | 9.17 | 2016-2025 | |
| 78 | Chris Tillman | 9.17 | 2010-2020 | |
| 80 | Wade Davis | 9.16 | 2009-2020 | |
| 80 | Edinson Volquez | 9.16 | 2008-2020 | |
| 82 | Rich Harden | 9.14 | 2004-2013 | |
| 82 | Eric O'Flaherty | 9.14 | 2007-2016 | |
| 84 | Felix Hernandez | 9.13 | 2005-2021 | |
| 85 | Manny Parra | 9.12 | 2007-2016 | |
| 86 | Wilmer Font | 9.10 | 2010-2020 | |
| 87 | Corbin Burnes# | 9.09 | 2020-2025 | |
| 87 | Sean Marshall | 9.09 | 2007-2016 | |
| 89 | Matt Moore# | 9.08 | 2012-2025 | |
| 90 | Cole Hamels | 9.07 | 2007-2022 | |
| 90 | Chad Billingsley | 9.07 | 2007-2015 | |
| 92 | Luis Severino# | 9.05 | 2016-2025 | |
| 93 | Gio Gonzalez | 9.02 | 2010-2022 | |
| 94 | Brandon Woodruff# | 9.00 | 2015-2025 | |
| 94 | Jacob Degrom# | 9.00 | 2012-2025 | |
| 96 | Dylan Cease# | 8.99 | 2015-2025 | |
| 96 | Robbie Ross Jr. | 8.99 | 2010-2017 | |
| 98 | Ubaldo Jimenez | 8.98 | 2010-2020 | |
| 99 | A.J. Griffin | 8.97 | 2014-2017 | |
| 99 | Oliver Drake | 8.97 | 2010-2022 |
