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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Michael Hermosillo# | 87 | 2020-2024 | |
| 2 | Guillermo Heredia# | 55 | 2017-2024 | |
| 3 | Clint Frazier | 50 | 2017-2019 | |
| 4 | Tyler Collins | 49 | 2015-2019 | |
| 5 | Keon Broxton | 44 | 2016-2021 | |
| 6 | Brandon Barnes | 41 | 2015-2021 | |
| 7 | Justin Maxwell | 40 | 2014-2017 | |
| 7 | Corey Ray# | 40 | 2018-2024 | |
| 9 | Byron Buxton# | 36 | 2014-2018 | |
| 10 | Cedric Mullins# | 35 | 2020-2021 | |
| 11 | Matthew Den Dekker | 34 | 2013-2021 | |
| 11 | Kirk Nieuwenhuis | 34 | 2013-2018 | |
| 13 | Jordan Walker# | 33 | 2023-2025 | |
| 14 | Sam Hilliard# | 32 | 2023-2024 | |
| 15 | Daz Cameron# | 29 | 2018-2025 | |
| 15 | Collin Cowgill | 29 | 2013-2021 | |
| 15 | Blake Tekotte | 29 | 2013-2017 | |
| 15 | Alex Verdugo# | 29 | 2018-2019 | |
| 19 | Micker Adolfo# | 28 | 2017-2022 | |
| 19 | Herschel Powell | 28 | 2017-2023 | |
| 19 | Luis Robert Jr.# | 28 | 2020-2021 | |
| 22 | Leonys Martin | 27 | 2013-2019 | |
| 23 | Brian Bogusevic | 26 | 2013-2018 | |
| 23 | Shane Robinson | 26 | 2014-2016 | |
| 25 | Kyle Lewis# | 25 | 2020-2025 | |
| 25 | George Valera# | 25 | 2020-2024 | |
| 27 | Desmond Jennings | 24 | 2018-2018 | |
| 28 | Ramon Laureano# | 23 | 2018-2024 | |
| 29 | Mike Gerber | 22 | 2016-2021 | |
| 29 | Pedro Leon# | 22 | 2023-2025 | |
| 29 | Heliot Ramos# | 22 | 2021-2022 | |
| 29 | Jacob Robson# | 22 | 2020-2022 | |
| 33 | Jose Azocar# | 21 | 2022-2024 | |
| 33 | Chris Bostick | 21 | 2019-2022 | |
| 33 | Darren Ford | 21 | 2013-2018 | |
| 33 | Sal Frelick# | 21 | 2023-2025 | |
| 33 | Cole Gillespie | 21 | 2016-2019 | |
| 33 | Brandon Nimmo# | 21 | 2017-2018 | |
| 33 | Dustin Peterson# | 21 | 2017-2025 | |
| 33 | Taylor Trammell# | 21 | 2018-2021 | |
| 33 | Rickie Weeks Jr. | 21 | 2016-2017 | |
| 42 | Paulo Orlando | 20 | 2014-2020 | |
| 42 | Drew Robinson | 20 | 2019-2020 | |
| 42 | Mike Tauchman# | 20 | 2018-2023 | |
| 45 | Gorkys Hernandez | 19 | 2013-2017 | |
| 45 | Jack Lopez# | 19 | 2020-2025 | |
| 45 | Jiandido Tromp | 19 | 2019-2019 | |
| 48 | Andrew Aplin | 18 | 2015-2021 | |
| 48 | Michael Choice | 18 | 2013-2016 | |
| 48 | Garrett Mitchell# | 18 | 2023-2023 | |
| 51 | Eric Fryer | 17 | 2013-2017 | |
| 51 | Jacoby Jones | 17 | 2017-2023 | |
| 51 | Eury Perez | 17 | 2014-2019 | |
| 51 | Cesar Puello | 17 | 2013-2022 | |
| 55 | Engel Beltre | 16 | 2013-2018 | |
| 55 | Rafael Ortega# | 16 | 2015-2021 | |
| 55 | James Ramsey | 16 | 2015-2018 | |
| 58 | Jorge Barrosa# | 15 | 2023-2025 | |
| 58 | Ryan Brett | 15 | 2014-2019 | |
| 58 | Darrell Ceciliani | 15 | 2015-2016 | |
| 58 | Jeremy Hazelbaker | 15 | 2017-2017 | |
| 58 | Enrique Hernandez# | 15 | 2015-2020 | |
| 58 | Ryan LaMarre | 15 | 2016-2017 | |
| 58 | J.D. Martinez# | 15 | 2013-2014 | |
| 58 | Zach Watson# | 15 | 2022-2022 | |
| 66 | Harrison Bader# | 14 | 2017-2021 | |
| 66 | Gregor Blanco | 14 | 2017-2020 | |
| 66 | Joey Butler | 14 | 2014-2016 | |
| 66 | Greg Golson | 14 | 2013-2016 | |
| 66 | Anthony Gose# | 14 | 2016-2018 | |
| 66 | Brandon Jacobs | 14 | 2015-2016 | |
| 66 | Michael A. Taylor# | 14 | 2019-2024 | |
| 66 | Andrew Toles | 14 | 2018-2021 | |
| 74 | Kyle Isbel# | 13 | 2021-2022 | |
| 74 | Ryan Lollis | 13 | 2013-2018 | |
| 74 | Mark Payton# | 13 | 2018-2025 | |
| 74 | Eddy Rodriguez | 13 | 2014-2017 | |
| 78 | Rafael Bautista | 12 | 2023-2023 | |
| 78 | Dairon Blanco# | 12 | 2022-2023 | |
| 78 | Michael Gettys# | 12 | 2017-2017 | |
| 78 | Steven Selsky | 12 | 2016-2017 | |
| 82 | Greg Allen# | 11 | 2023-2025 | |
| 82 | Albert Almora# | 11 | 2017-2024 | |
| 82 | Corbin Carroll# | 11 | 2023-2024 | |
| 82 | Jake Cave# | 11 | 2013-2018 | |
| 82 | Franchy Cordero# | 11 | 2018-2025 | |
| 82 | Colton Cowser# | 11 | 2023-2024 | |
| 82 | Slade Heathcott | 11 | 2018-2018 | |
| 82 | Leonardo Heras | 11 | 2015-2015 | |
| 82 | Aaron Hicks# | 11 | 2022-2023 | |
| 82 | Brandon Lockridge# | 11 | 2021-2025 | |
| 82 | Tyrone Taylor# | 11 | 2016-2019 | |
| 93 | Anthony Alford# | 10 | 2020-2025 | |
| 93 | Tony Campana | 10 | 2014-2014 | |
| 93 | Pete Crow-Armstrong# | 10 | 2024-2024 | |
| 93 | Todd Cunningham | 10 | 2013-2020 | |
| 93 | Antoine Duplantis | 10 | 2022-2023 | |
| 93 | Dominic Fletcher# | 10 | 2023-2025 | |
| 93 | Randal Grichuk# | 10 | 2014-2024 | |
| 93 | Trent Grisham# | 10 | 2019-2024 |
