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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | K | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Carlos Rodon# | 34 | 2016-2019 | |
| 2 | Miguel A. Gonzalez | 31 | 2014-2018 | |
| 3 | Alex Meyer | 28 | 2013-2017 | |
| 4 | Cory Gearrin | 23 | 2013-2020 | |
| 5 | Robbie Erlin# | 20 | 2013-2018 | |
| 5 | Josh James# | 20 | 2019-2020 | |
| 5 | Eric Jokisch# | 20 | 2018-2023 | |
| 5 | Julio Teheran | 20 | 2013-2013 | |
| 9 | Clay Buchholz | 18 | 2013-2021 | |
| 9 | Anthony DeSclafani# | 18 | 2015-2025 | |
| 9 | Danny Salazar | 18 | 2014-2017 | |
| 12 | Davis Daniel# | 17 | 2022-2025 | |
| 12 | Kirby Yates# | 17 | 2014-2019 | |
| 14 | Jhony Brito# | 16 | 2024-2025 | |
| 14 | Madison Bumgarner | 16 | 2013-2013 | |
| 14 | Carl Edwards Jr.# | 16 | 2016-2017 | |
| 14 | Scott Moss | 16 | 2018-2024 | |
| 18 | Scott Alexander# | 15 | 2014-2024 | |
| 18 | Jeremy Hefner | 15 | 2013-2017 | |
| 18 | Casey Kelly# | 15 | 2021-2024 | |
| 18 | Ryne Nelson# | 15 | 2023-2024 | |
| 22 | Spencer Arrighetti# | 14 | 2025-2025 | |
| 22 | Heath Hembree | 14 | 2015-2019 | |
| 24 | David Buchanan# | 13 | 2015-2021 | |
| 24 | Conor Fisk | 13 | 2019-2021 | |
| 24 | Jake Kalish# | 13 | 2019-2023 | |
| 24 | Penn Murfee# | 13 | 2020-2025 | |
| 24 | A.J. Puk# | 13 | 2019-2021 | |
| 24 | Taylor Williams | 13 | 2018-2020 | |
| 30 | Jose Alvarez | 12 | 2015-2021 | |
| 30 | Barrett Astin | 12 | 2017-2018 | |
| 30 | Paul Campbell# | 12 | 2020-2025 | |
| 30 | Tyler Glasnow# | 12 | 2016-2021 | |
| 30 | Will Hibbs | 12 | 2020-2021 | |
| 30 | Cole Irvin# | 12 | 2025-2025 | |
| 30 | Merrill Kelly# | 12 | 2019-2025 | |
| 30 | Blaine Knight# | 12 | 2023-2025 | |
| 38 | Buddy Boshers | 11 | 2016-2021 | |
| 38 | Matt Brash# | 11 | 2022-2025 | |
| 38 | Hunter Brown# | 11 | 2022-2024 | |
| 38 | Brett Cecil | 11 | 2014-2014 | |
| 38 | Luiz Gohara | 11 | 2018-2021 | |
| 38 | Michael Grove# | 11 | 2023-2024 | |
| 38 | Grayson Long | 11 | 2018-2018 | |
| 38 | Collin McHugh | 11 | 2013-2015 | |
| 38 | Casey Mize# | 11 | 2020-2022 | |
| 38 | Alex Reyes | 11 | 2017-2024 | |
| 38 | Jordan Stephens | 11 | 2016-2024 | |
| 49 | Walker Buehler# | 10 | 2018-2020 | |
| 49 | Buck Farmer# | 10 | 2019-2025 | |
| 49 | Luke Farrell# | 10 | 2020-2025 | |
| 49 | Christian Friedrich | 10 | 2014-2021 | |
| 49 | Shintaro Fujinami# | 10 | 2023-2025 | |
| 49 | MacKenzie Gore# | 10 | 2023-2024 | |
| 49 | Jorge Lopez# | 10 | 2015-2020 | |
| 49 | Roberto Perez | 10 | 2017-2017 | |
| 49 | Dillon Peters# | 10 | 2018-2022 | |
| 49 | Yankory Pimentel | 10 | 2020-2021 | |
| 49 | Max Povse | 10 | 2018-2021 | |
| 49 | Austin Pruitt# | 10 | 2017-2024 | |
| 49 | Jefry Rodriguez# | 10 | 2020-2025 | |
| 49 | Ryan Rolison# | 10 | 2022-2023 | |
| 49 | Sal Romano# | 10 | 2017-2025 | |
| 64 | Brady Basso# | 9 | 2024-2024 | |
| 64 | Brandon Beachy | 9 | 2015-2018 | |
| 64 | Jordan Guerrero# | 9 | 2018-2020 | |
| 64 | Carlos Hernandez# | 9 | 2022-2025 | |
| 64 | Joe Kelly# | 9 | 2015-2021 | |
| 64 | Michael Kopech# | 9 | 2019-2020 | |
| 64 | Cory Luebke | 9 | 2013-2016 | |
| 64 | Dennis Santana# | 9 | 2019-2024 | |
| 64 | Charlie Shirek | 9 | 2015-2016 | |
| 64 | Brady Singer# | 9 | 2020-2024 | |
| 64 | Mitch Spence# | 9 | 2023-2025 | |
| 64 | Marcus Stroman# | 9 | 2013-2025 | |
| 64 | Jake Thompson | 9 | 2016-2020 | |
| 64 | Steven Wright | 9 | 2015-2021 | |
| 78 | Tim Cate# | 8 | 2022-2022 | |
| 78 | Cade Cavalli# | 8 | 2023-2025 | |
| 78 | Taylor Clarke# | 8 | 2021-2025 | |
| 78 | Scott Elbert | 8 | 2014-2016 | |
| 78 | Casey Fien | 8 | 2013-2013 | |
| 78 | Miguel Gonzalez | 8 | 2018-2018 | |
| 78 | Reymin Guduan | 8 | 2018-2021 | |
| 78 | Marcus Hatley | 8 | 2014-2016 | |
| 78 | Michael Kirkman | 8 | 2013-2014 | |
| 78 | Adam Liberatore | 8 | 2014-2020 | |
| 78 | Phil Maton# | 8 | 2017-2019 | |
| 78 | Yuki Matsui# | 8 | 2024-2025 | |
| 78 | Brendan McCurry | 8 | 2018-2019 | |
| 78 | Ricky Nolasco | 8 | 2016-2016 | |
| 78 | Jose Ortega | 8 | 2014-2017 | |
| 78 | Thomas Pannone# | 8 | 2019-2025 | |
| 78 | Luis Perdomo# | 8 | 2017-2018 | |
| 78 | Zach Putnam | 8 | 2014-2019 | |
| 78 | Drew Rucinski# | 8 | 2018-2025 | |
| 97 | Tristan Archer | 7 | 2017-2020 | |
| 97 | Vicente Campos | 7 | 2018-2018 | |
| 97 | Xzavion Curry# | 7 | 2024-2024 | |
| 97 | Shane Dawson | 7 | 2020-2021 |
