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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Ibandel Isabel | 111 | 2018-2022 | |
| 2 | Josh Lester# | 104 | 2019-2023 | |
| 3 | Franklin Barreto# | 95 | 2016-2024 | |
| 4 | Alexander Palma | 91 | 2019-2023 | |
| 5 | Bobby Coyle | 90 | 2013-2016 | |
| 5 | Aderlin Rodriguez | 90 | 2016-2024 | |
| 7 | Peter O'Brien | 83 | 2015-2018 | |
| 8 | Ryan Cordell | 82 | 2015-2022 | |
| 9 | Luken Baker# | 78 | 2016-2018 | |
| 10 | Michael Gettys# | 70 | 2019-2021 | |
| 11 | Connor Panas | 69 | 2018-2021 | |
| 12 | Tyler Hardman# | 67 | 2023-2025 | |
| 13 | Clint Coulter# | 64 | 2017-2023 | |
| 14 | D.J. Peterson | 62 | 2015-2023 | |
| 14 | Brett Sullivan# | 62 | 2018-2024 | |
| 16 | Royce Bolinger | 59 | 2018-2021 | |
| 16 | Gorman Erickson | 59 | 2013-2015 | |
| 16 | Telvin Nash | 59 | 2015-2019 | |
| 19 | Jaylin Davis# | 57 | 2016-2021 | |
| 19 | Gavin LaValley | 57 | 2017-2021 | |
| 21 | Stetson Allie | 55 | 2017-2020 | |
| 21 | Mandy Alvarez# | 55 | 2019-2023 | |
| 21 | Daniel Butler | 55 | 2013-2017 | |
| 21 | Zach Walters | 55 | 2013-2018 | |
| 25 | Dilson Herrera | 54 | 2019-2022 | |
| 25 | Victor Roache | 54 | 2016-2019 | |
| 25 | Ramon Urias# | 54 | 2020-2021 | |
| 28 | Malcom Nunez# | 53 | 2022-2025 | |
| 29 | Nick Evans | 52 | 2014-2016 | |
| 29 | Daniel Kihle | 52 | 2018-2021 | |
| 29 | Jordy Lara | 52 | 2018-2021 | |
| 32 | Michael Almanzar | 51 | 2014-2017 | |
| 32 | Zach Collier | 51 | 2014-2019 | |
| 32 | Tyler Marincov | 51 | 2017-2018 | |
| 35 | Joey Gallo# | 50 | 2014-2015 | |
| 35 | Jacoby Jones | 50 | 2017-2022 | |
| 37 | Brennen Davis# | 49 | 2021-2025 | |
| 37 | Juan Diaz | 49 | 2014-2017 | |
| 37 | Dawel Lugo | 49 | 2016-2021 | |
| 40 | Zac Cook# | 48 | 2024-2025 | |
| 40 | Fernando Tatis Jr.# | 48 | 2018-2019 | |
| 42 | Jose Barrero# | 47 | 2021-2025 | |
| 42 | Willi Castro# | 47 | 2018-2021 | |
| 42 | Cade Doughty# | 47 | 2023-2024 | |
| 42 | Hector Gomez | 47 | 2013-2017 | |
| 42 | Ernesto Mejia | 47 | 2013-2021 | |
| 42 | Ryan Schimpf | 47 | 2013-2016 | |
| 42 | Taylor Walls# | 47 | 2020-2024 | |
| 49 | Michael Busch# | 46 | 2021-2023 | |
| 49 | Lucas Erceg# | 46 | 2019-2023 | |
| 49 | Gilbert Gomez | 46 | 2014-2019 | |
| 49 | Jahmai Jones# | 46 | 2018-2021 | |
| 53 | Miguel Aparicio# | 45 | 2023-2025 | |
| 53 | Jordan Diaz# | 45 | 2023-2025 | |
| 53 | Jose Herrera# | 45 | 2019-2023 | |
| 53 | Derek Hill# | 45 | 2020-2023 | |
| 53 | Connor Lien | 45 | 2016-2020 | |
| 53 | Drew Vettleson | 45 | 2014-2019 | |
| 59 | Tres Barrera# | 44 | 2019-2025 | |
| 59 | Marcos Castanon# | 44 | 2024-2025 | |
| 59 | Niko Goodrum# | 44 | 2014-2018 | |
| 62 | Jodd Carter | 43 | 2016-2022 | |
| 62 | Sonny DiChiara# | 43 | 2024-2025 | |
| 62 | Sherman Johnson | 43 | 2018-2022 | |
| 62 | Henry Ramos# | 43 | 2015-2021 | |
| 62 | Jared Young# | 43 | 2019-2024 | |
| 67 | John Aiello# | 42 | 2023-2025 | |
| 67 | Sebastian Elizalde | 42 | 2015-2021 | |
| 67 | Chris Paul | 42 | 2019-2024 | |
| 67 | Zack Zehner | 42 | 2017-2022 | |
| 71 | Kody Clemens# | 41 | 2019-2021 | |
| 71 | Monte Harrison | 41 | 2021-2024 | |
| 71 | Cooper Hummel# | 41 | 2020-2023 | |
| 71 | Chris Meyers# | 41 | 2024-2025 | |
| 71 | Dom Nunez# | 41 | 2020-2025 | |
| 71 | Jiandido Tromp | 41 | 2014-2019 | |
| 77 | Eliezer Alvarez | 40 | 2016-2022 | |
| 77 | Luis Barrera | 40 | 2020-2023 | |
| 77 | Brett Eibner | 40 | 2013-2016 | |
| 77 | Agustin Ramirez# | 40 | 2024-2025 | |
| 77 | Dayron Varona | 40 | 2016-2018 | |
| 82 | Gabriel Guerrero | 39 | 2015-2022 | |
| 82 | Darwin Perez | 39 | 2013-2015 | |
| 84 | Kevin Cornelius | 38 | 2018-2019 | |
| 84 | Derek Dietrich | 38 | 2013-2015 | |
| 84 | Jim Haley# | 38 | 2019-2023 | |
| 84 | Patrick Leonard | 38 | 2014-2021 | |
| 88 | Jack Lopez# | 37 | 2019-2024 | |
| 88 | Jacob Stallings# | 37 | 2013-2018 | |
| 90 | Yu Chang# | 36 | 2017-2020 | |
| 90 | Erick Mejia | 36 | 2018-2024 | |
| 90 | Joe Odom | 36 | 2014-2022 | |
| 90 | Ronny Rodriguez | 36 | 2013-2023 | |
| 90 | Tim Wheeler | 36 | 2014-2017 | |
| 95 | Eric Jagielo | 35 | 2016-2019 | |
| 95 | Tyler Moore | 35 | 2015-2017 | |
| 95 | A.J. Murray | 35 | 2018-2021 | |
| 95 | Jose Peroza# | 35 | 2023-2025 | |
| 95 | Pablo Reyes# | 35 | 2018-2022 | |
| 100 | Josh Fellhauer | 34 | 2013-2015 |
