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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, Royber | SP | London Wolverines | 25 | 04/10/2001 | Guarenas | VEN | Right | Right | 6' 3" | 205 lbs | - |
| Samaniego, Tyler | RP | Harrisburg Senators | 27 | 01/30/1999 | Huntsville | USA | Right | Left | 6' 4" | 205 lbs | - |
| Sanmartin, Reiver | SP | Quebec Castors | 30 | 04/15/1996 | Cartagena | COL | Left | Left | 6' 2" | 155 lbs | - |
| Santana, Adrian | SS | Harrisburg Senators | 20 | 07/18/2005 | Miami | USA | Switch | Right | 6' 0" | 160 lbs | - |
| Santucci, Jonathan | SP | Madison Millers | 23 | 12/28/2002 | Leominster | USA | Left | Left | 6' 2" | 205 lbs | - |
| Scherff, Alex | RP | Free Agent | 28 | 02/05/1998 | Unknown | USA | Switch | Right | 6' 3" | 210 lbs | - |
| Schiavone, Jason | C | Dayton Dragons | 23 | 03/19/2003 | Unknown | USA | Right | Right | 6' 2" | 205 lbs | - |
| Schomberg, Will | SP | Trenton Thunder | 25 | 01/30/2001 | Clemmons | USA | Right | Right | 5' 10" | 190 lbs | - |
| Schreffler, Troy | LF | Harrisburg Senators | 25 | 10/27/2000 | Unknown | USA | Right | Right | 6' 1" | 190 lbs | - |
| Schultz, Thomas | RP | Harrisburg Senators | 26 | 08/03/1999 | Unknown | USA | Right | Right | 6' 6" | 215 lbs | - |
| Scull, Anthony | CF | Plattsburgh Beacons | 22 | 01/26/2004 | Havana | CUB | Left | Left | 6' 0" | 165 lbs | - |
| Selby, Colin | RP | Dayton Dragons | 28 | 10/24/1997 | Chesapeake | USA | Right | Right | 6' 1" | 220 lbs | - |
| Seymour, Carson | SP | London Wolverines | 27 | 12/16/1998 | Poway | USA | Right | Right | 6' 5" | 250 lbs | - |
| Shackelford, Aaron | 1B | Champagne Black Bears | 29 | 10/16/1996 | Murrieta | USA | Left | Right | 5' 10" | 205 lbs | - |
| Sharp, Jacob | C | Plattsburgh Beacons | 24 | 09/15/2001 | La Mirada | USA | Right | Right | 5' 11" | 195 lbs | - |
| Shaw, Sam | LF | Trenton Thunder | 21 | 02/26/2005 | Victoria | CAN | Right | Right | 5' 10" | 180 lbs | - |
| Shewmake, Braden | 2B | London Wolverines | 28 | 11/19/1997 | Wylie | USA | Left | Right | 6' 4" | 190 lbs | - |
| Shojinaga, Kodey | C | Quebec Castors | 23 | 02/22/2003 | Honolulu | USA | Right | Right | 5' 10" | 190 lbs | - |
| Shore, Logan | SP | Madison Millers | 31 | 12/28/1994 | Coon Rapids | USA | Right | Right | 6' 2" | 210 lbs | - |
| Short, Avery | SP | Champagne Black Bears | 25 | 03/14/2001 | Indianapolis | USA | Right | Left | 6' 1" | 205 lbs | - |
| Siani, Michael | CF | Trenton Thunder | 27 | 07/16/1999 | Glenside | USA | Left | Left | 6' 1" | 180 lbs | - |
| Sogard, Nick | 2B | Quebec Castors | 28 | 09/09/1997 | Sacramento | USA | Switch | Right | 6' 1" | 185 lbs | - |
| Solak, Nick | LF | Canton Cutters | 31 | 01/11/1995 | Woodridge | USA | Right | Right | 5' 10" | 185 lbs | - |
| Solomon, Peter | RP | Free Agent | 29 | 08/16/1996 | Unknown | USA | Right | Right | 6' 4" | 205 lbs | - |
| Soto, Charlee | SP | Dayton Dragons | 20 | 08/31/2005 | Kissimmee | USA | Switch | Right | 6' 5" | 210 lbs | - |
| Southisene, Ty | SS | Trenton Thunder | 21 | 07/08/2005 | Henderson | USA | Right | Right | 5' 9" | 160 lbs | - |
| Stauffer, Adam | SP | Hempstead Flying Dutchmen | 27 | 01/13/1999 | Coatesville | USA | Right | Right | 6' 7" | 240 lbs | - |
| Strowd, Kade | RP | Quebec Castors | 28 | 09/17/1997 | Fort Worth | USA | Right | Right | 6' 2" | 175 lbs | - |
| Sullivan, Joseph | RF | Dayton Dragons | 24 | 07/01/2002 | Birmingham | USA | Left | Left | 5' 11" | 200 lbs | - |
| Sullivan, Sean | RP | Harrisburg Senators | 25 | 08/02/2000 | Woodland Hills | USA | Right | Right | 6' 1" | 175 lbs | - |
| Swan, Eriq | SP | London Wolverines | 24 | 10/31/2001 | Murfreesboro | USA | Right | Right | 6' 6" | 240 lbs | - |
