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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sadzeck, Connor | RP | San Jose Thorns | 33 | 10/01/1991 | Crystal Lake | USA | Right | Right | 6' 5" | 210 lbs | - |
| Sands, Donny | C | Amarillo Armadillos | 28 | 05/16/1996 | Unknown | USA | Right | Right | 6' 2" | 200 lbs | - |
| Santiago, Glenn | SS | Tulsa T-Bones | 24 | 12/14/2000 | Guanica | PUR | Right | Right | 6' 0" | 165 lbs | - |
| Schlittler, Cam | RP | Tempe Titans | 24 | 02/05/2001 | Unknown | USA | Right | Right | 6' 6" | 210 lbs | - |
| Schneemann, Daniel | 3B | Roswell UFO | 28 | 01/23/1997 | Chula Vista | USA | Left | Right | 6' 1" | 185 lbs | - |
| Scott, Stephen | C | Fresno Grizzlies | 27 | 05/23/1997 | Unknown | USA | Left | Right | 6' 1" | 180 lbs | - |
| Sears, Ben | RP | Roswell UFO | 24 | 06/15/2000 | Bremen | USA | Right | Right | 6' 5" | 200 lbs | - |
| Serna, Jared | 2B | Tempe Titans | 22 | 06/01/2002 | Guaymas | MEX | Right | Right | 5' 8" | 170 lbs | - |
| Shreve, Ryan | SP | Amarillo Armadillos | 26 | 06/23/1998 | Los Angeles | USA | Right | Right | 6' 6" | 215 lbs | - |
| Sierra, Magneuris | RF | Amarillo Armadillos | 29 | 04/07/1996 | San Cristóbal | DOM | Left | Left | 5' 11" | 170 lbs | - |
| Sikkema, T.J. | RP | Fresno Grizzlies | 26 | 07/25/1998 | De Witt | USA | Left | Left | 6' 0" | 220 lbs | - |
| Sims, Lucas | RP | San Jose Thorns | 30 | 05/10/1994 | Lawrenceville | USA | Right | Right | 6' 3" | 205 lbs | - |
| Smith, Cade | SP | Tempe Titans | 23 | 04/09/2002 | Southaven | USA | Left | Right | 6' 1" | 190 lbs | - |
| Smith, Dominic | 1B | Plano-Frisco Roughriders | 29 | 06/15/1995 | Los Angeles | USA | Left | Left | 6' 1" | 205 lbs | - |
| Smith, Drew | RP | Midland Rattlers | 31 | 09/24/1993 | Unknown | USA | Right | Right | 6' 2" | 195 lbs | - |
| Smith-Shawver, AJ | SP | Midland Rattlers | 22 | 08/20/2002 | Fort Worth | USA | Right | Right | 6' 3" | 205 lbs | - |
| Spacke, Dylan | RP | Fresno Grizzlies | 27 | 03/11/1998 | San Diego | USA | Switch | Right | 6' 0" | 180 lbs | - |
| Spiers, Carson | RP | Fresno Grizzlies | 27 | 11/11/1997 | Unknown | USA | Right | Right | 6' 3" | 205 lbs | - |
| Stephens, Jackson | RP | Midland Rattlers | 30 | 05/11/1994 | Oxford | USA | Right | Right | 6' 3" | 215 lbs | - |
| Stevens, Chad | SS | Amarillo Armadillos | 26 | 02/03/1999 | Walnut Creek | USA | Right | Right | 6' 4" | 215 lbs | - |
| Stewart, Sal | 3B | Plano-Frisco Roughriders | 21 | 12/07/2003 | Unknown | USA | Right | Right | 6' 3" | 215 lbs | - |
| Straw, Myles | CF | Plano-Frisco Roughriders | 30 | 10/17/1994 | Unknown | USA | Right | Right | 5' 10" | 195 lbs | - |
| Strotman, Drew | RP | Fresno Grizzlies | 28 | 09/03/1996 | Sunnyvale | USA | Right | Right | 6' 3" | 200 lbs | - |
| Sullivan, Sean | SP | Plano-Frisco Roughriders | 22 | 07/22/2002 | Andover | USA | Right | Left | 6' 4" | 190 lbs | - |
