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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Santana, Cristian | 3B | Fresno Grizzlies | 28 | 02/24/1997 | San Cristóbal | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Santiago, Glenn | SS | Tulsa T-Bones | 24 | 12/14/2000 | Guanica | PUR | Right | Right | 6' 0" | 165 lbs | - |
| Sasaki, Shane | CF | Roswell UFO | 25 | 07/01/2000 | Mililani Town | USA | Right | Right | 6' 0" | 165 lbs | - |
| Schofield-Sam, T.J. | 3B | Plano-Frisco Roughriders | 24 | 06/20/2001 | Unknown | CAN | Left | Right | 6' 1" | 185 lbs | - |
| Schultz, Noah | SP | Amarillo Armadillos | 22 | 08/05/2003 | Unknown | USA | Left | Left | 6' 9" | 225 lbs | - |
| Scott, Jordan | RF | Tempe Titans | 28 | 05/23/1997 | Unknown | USA | Switch | Right | 6' 0" | 215 lbs | - |
| Scott, Stephen | C | Fresno Grizzlies | 28 | 05/23/1997 | Unknown | USA | Left | Right | 6' 1" | 180 lbs | - |
| Seelinger, Matt | RP | Midland Rattlers | 30 | 04/19/1995 | Westbury | USA | Right | Right | 6' 3" | 190 lbs | - |
| Servideo, Anthony | SS | Tempe Titans | 26 | 03/11/1999 | Jupiter | USA | Left | Right | 5' 10" | 175 lbs | - |
| Serwinowski, Adam | SP | Plano-Frisco Roughriders | 21 | 06/07/2004 | Unknown | USA | Left | Left | 6' 5" | 190 lbs | - |
| Shugart, Chase | RP | San Jose Thorns | 28 | 10/24/1996 | Bridge City | USA | Right | Right | 5' 10" | 180 lbs | - |
| Simas, Karson | 3B | Fresno Grizzlies | 24 | 06/02/2001 | Fresno | USA | Right | Right | 6' 6" | 175 lbs | - |
| Simmons, Kendall | SS | Fresno Grizzlies | 25 | 04/11/2000 | Macon | USA | Right | Right | 6' 2" | 180 lbs | - |
| Sisneros, Cameron | 1B | Tempe Titans | 24 | 06/01/2001 | Littleton | USA | Left | Left | 6' 2" | 230 lbs | - |
| Smith, Adam | RP | San Jose Thorns | 25 | 05/09/2000 | West Chester | USA | Right | Right | 6' 2" | 180 lbs | - |
| Smith, D'Andre | 2B | San Jose Thorns | 24 | 05/10/2001 | Atwater | USA | Right | Right | 5' 9" | 180 lbs | - |
| Smith, Dominic | 1B | Plano-Frisco Roughriders | 30 | 06/15/1995 | Los Angeles | USA | Left | Left | 6' 1" | 205 lbs | - |
| Smith, Drew | RP | Midland Rattlers | 32 | 09/24/1993 | Unknown | USA | Right | Right | 6' 2" | 195 lbs | - |
| Smith, Marcus | CF | San Jose Thorns | 25 | 09/11/2000 | Kansas City | USA | Left | Left | 5' 11" | 190 lbs | - |
| Snelling, Robby | SP | Amarillo Armadillos | 21 | 12/19/2003 | Unknown | USA | Right | Left | 6' 3" | 220 lbs | - |
| Solometo, Anthony | SP | Amarillo Armadillos | 22 | 12/02/2002 | Unknown | USA | Left | Left | 6' 5" | 220 lbs | - |
| Sparks, Lamar | LF | Plano-Frisco Roughriders | 27 | 09/26/1998 | Unknown | USA | Right | Right | 6' 2" | 175 lbs | - |
| Spiers, Carson | SP | Fresno Grizzlies | 27 | 11/11/1997 | Unknown | USA | Right | Right | 6' 3" | 205 lbs | - |
| Stefanic, Michael | 2B | Fresno Grizzlies | 29 | 02/24/1996 | Teutopolis | USA | Right | Right | 5' 10" | 180 lbs | - |
| Stephan, Josh | SP | Midland Rattlers | 23 | 11/01/2001 | Grand Prairie | USA | Right | Right | 6' 3" | 185 lbs | - |
| Stovall, Hunter | 2B | Plano-Frisco Roughriders | 29 | 09/05/1996 | Pelham | USA | Right | Right | 5' 8" | 175 lbs | - |
| Stubbs, Garrett | C | San Jose Thorns | 32 | 05/26/1993 | Unknown | USA | Left | Right | 5' 10" | 195 lbs | - |
| Sullivan, Sean | SP | Plano-Frisco Roughriders | 23 | 07/22/2002 | Andover | USA | Right | Left | 6' 4" | 190 lbs | - |
