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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabol, Blake | LF | Fresno Grizzlies | 28 | 01/07/1998 | Aliso Viejo | USA | Left | Right | 6' 4" | 215 lbs | - |
| Sanchez, Jadiel | RF | Roswell UFO | 25 | 05/10/2001 | Arroyo | PUR | Switch | Right | 6' 2" | 185 lbs | - |
| Sandridge, Jayvien | RP | San Jose Thorns | 27 | 02/11/1999 | Hagerstown | USA | Left | Left | 6' 5" | 220 lbs | - |
| Santiago, Glenn | SS | Tulsa T-Bones | 25 | 12/14/2000 | Guanica | PUR | Right | Right | 6' 0" | 165 lbs | - |
| Santos, Victor | SP | Tulsa T-Bones | 25 | 07/12/2000 | Villa Tapia | DOM | Right | Right | 6' 1" | 190 lbs | - |
| Schofield-Sam, T.J. | 3B | Plano-Frisco Roughriders | 24 | 06/20/2001 | Unknown | CAN | Left | Right | 6' 1" | 185 lbs | - |
| Schultz, Noah | SP | Amarillo Armadillos | 22 | 08/05/2003 | Unknown | USA | Left | Left | 6' 9" | 225 lbs | - |
| Scott, Connor | CF | Midland Rattlers | 26 | 10/08/1999 | Tampa | USA | Left | Left | 6' 4" | 185 lbs | - |
| Scott, Jordan | RF | Tempe Titans | 28 | 05/23/1997 | Unknown | USA | Switch | Right | 6' 0" | 215 lbs | - |
| Scott, Stephen | C | Fresno Grizzlies | 28 | 05/23/1997 | Unknown | USA | Left | Right | 6' 1" | 180 lbs | - |
| Serwinowski, Adam | SP | Plano-Frisco Roughriders | 21 | 06/07/2004 | Unknown | USA | Left | Left | 6' 5" | 190 lbs | - |
| Simas, Karson | 3B | Fresno Grizzlies | 24 | 06/02/2001 | Fresno | USA | Right | Right | 6' 6" | 175 lbs | - |
| Simpson, Josh | SP | Roswell UFO | 28 | 08/19/1997 | Stafford | USA | Left | Left | 6' 2" | 190 lbs | - |
| Sisneros, Cameron | 1B | Tempe Titans | 24 | 06/01/2001 | Littleton | USA | Left | Left | 6' 2" | 230 lbs | - |
| Smith, Drew | RP | Midland Rattlers | 32 | 09/24/1993 | Unknown | USA | Right | Right | 6' 2" | 195 lbs | - |
| Smith, Hagen | SP | Amarillo Armadillos | 22 | 08/19/2003 | Bullard | USA | Left | Left | 6' 3" | 215 lbs | - |
| Snelling, Robby | SP | Amarillo Armadillos | 22 | 12/19/2003 | Unknown | USA | Right | Left | 6' 3" | 220 lbs | - |
| Speas, Alex | RP | Fresno Grizzlies | 28 | 03/04/1998 | Powder Springs | USA | Right | Right | 6' 4" | 195 lbs | - |
| Spiers, Carson | SP | Fresno Grizzlies | 28 | 11/11/1997 | Unknown | USA | Right | Right | 6' 3" | 205 lbs | - |
| Spikes, Ryan | 3B | San Jose Thorns | 23 | 03/13/2003 | Conyers | USA | Right | Right | 5' 9" | 185 lbs | - |
| Stashak, Cody | RP | Roswell UFO | 31 | 06/04/1994 | Unknown | USA | Right | Right | 6' 2" | 195 lbs | - |
| Stephan, Josh | SP | Midland Rattlers | 24 | 11/01/2001 | Grand Prairie | USA | Right | Right | 6' 3" | 185 lbs | - |
| Suero, Christopher | C | Roswell UFO | 22 | 01/27/2004 | New York | USA | Right | Right | 6' 0" | 205 lbs | - |
| Sullivan, Sean | SP | Plano-Frisco Roughriders | 23 | 07/22/2002 | Andover | USA | Right | Left | 6' 4" | 190 lbs | - |
