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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, Raimfer | CF | Dunedin Danger | 24 | 12/31/2000 | Ciudad Guayana | VEN | Right | Right | 6' 0" | 175 lbs | - |
| Scarborough, Caden | SP | Plant City Farmers | 20 | 04/01/2005 | Unknown | USA | Right | Right | 6' 5" | 185 lbs | - |
| Schiavone, Jason | C | Tampa Tigers | 22 | 03/19/2003 | Unknown | USA | Right | Right | 6' 2" | 205 lbs | - |
| Schlesinger, Rafe | RP | Dunedin Danger | 22 | 01/22/2003 | Holbrook | USA | Left | Left | 6' 3" | 200 lbs | - |
| Schobel, Tanner | 2B | Gainesville Gators | 24 | 06/04/2001 | Unknown | USA | Right | Right | 5' 10" | 170 lbs | - |
| Sena, Reidis | RP | Dunedin Danger | 24 | 04/07/2001 | Unknown | DOM | Right | Right | 5' 10" | 160 lbs | - |
| Serna, Luis | SP | Lakeland Catfish | 20 | 07/20/2004 | San Luis Río Colorado | MEX | Right | Right | 5' 11" | 145 lbs | - |
| Shockley, Dylan | C | Gainesville Gators | 28 | 04/10/1997 | Harrison | USA | Right | Right | 5' 11" | 195 lbs | - |
| Simon, Liam | RP | Vero Beach Blue Angels | 24 | 10/16/2000 | Unknown | USA | Right | Right | 6' 4" | 220 lbs | - |
| Simoneit, William | 1B | Vero Beach Blue Angels | 28 | 10/14/1996 | Glen Ellyn | USA | Right | Right | 6' 4" | 235 lbs | - |
| Smith, Chad C. | RP | St. Lucie Sand Gnats | 30 | 06/08/1995 | Bessemer | USA | Right | Right | 6' 4" | 205 lbs | - |
| Smith, Jaylen | RP | Daytona Firebirds | 25 | 11/05/1999 | Copperas Cove | USA | Left | Left | 5' 11" | 170 lbs | - |
| Smith, Parker | SP | Vero Beach Blue Angels | 22 | 03/05/2003 | Bellaire | USA | Right | Right | 6' 3" | 230 lbs | - |
| Spain, Garrett | CF | Daytona Firebirds | 24 | 09/21/2000 | Clarksville | USA | Left | Right | 5' 11" | 180 lbs | - |
| Sparks, Wyatt | SP | Tampa Tigers | 25 | 09/27/1999 | Aurora | USA | Right | Right | 6' 2" | 185 lbs | - |
| Sprague-Lott, Jared | SS | Dunedin Danger | 23 | 10/10/2001 | Philadelphia | USA | Right | Right | 6' 0" | 195 lbs | - |
| Stafura, Sammy | SS | Tampa Tigers | 20 | 11/15/2004 | Unknown | USA | Right | Right | 6' 0" | 185 lbs | - |
| Standlee, Brett | RP | St. Lucie Sand Gnats | 26 | 09/14/1998 | Tulsa | USA | Right | Right | 6' 4" | 225 lbs | - |
| Stanley, Hunter | RP | Free Agent | 27 | 08/25/1997 | Hammond | USA | Right | Right | 6' 0" | 190 lbs | - |
| Stowers, Josh | LF | Tampa Tigers | 28 | 02/25/1997 | Westchester | USA | Right | Right | 6' 0" | 200 lbs | - |
| Strohschein, Kevin | RF | Vero Beach Blue Angels | 27 | 07/25/1997 | MacDonough | USA | Right | Right | 6' 1" | 215 lbs | - |
| Strong, Hunter | RP | Vero Beach Blue Angels | 28 | 03/25/1997 | Sheridan | USA | Left | Left | 6' 1" | 205 lbs | - |
| Strong, Jackson | LF | Lakeland Catfish | 21 | 08/26/2003 | West Seneca | USA | Left | Left | 6' 1" | 185 lbs | - |
| Stumpo, Mitchell | RP | Gainesville Gators | 29 | 06/17/1996 | Raleigh | USA | Right | Right | 6' 2" | 205 lbs | - |
| Suisbel, Luis | 3B | Dunedin Danger | 22 | 05/23/2003 | Valencia | VEN | Switch | Right | 6' 1" | 190 lbs | - |
| Sullivan, Joseph | RF | Tampa Tigers | 23 | 07/01/2002 | Birmingham | USA | Left | Left | 5' 11" | 200 lbs | - |
| Sykora, Travis | SP | Plant City Farmers | 21 | 04/28/2004 | Round Rock | USA | Right | Right | 6' 6" | 220 lbs | - |
| Szykowny, Charlie | 3B | St. Lucie Sand Gnats | 25 | 06/30/2000 | Colorado Springs | USA | Left | Right | 6' 4" | 225 lbs | - |
