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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saladin, Darlin | SP | Daytona Firebirds | 22 | 12/28/2002 | San Pedro de Macorís | DOM | Right | Right | 5' 11" | 150 lbs | - |
| Sales, RJ | SP | Lakeland Catfish | 21 | 07/22/2003 | Pinehurst | USA | Right | Right | 6' 0" | 165 lbs | - |
| Salinas, Raimfer | CF | Dunedin Danger | 24 | 12/31/2000 | Ciudad Guayana | VEN | Right | Right | 6' 0" | 175 lbs | - |
| Saucke II, Casey | RF | Dunedin Danger | 21 | 07/24/2003 | Rochester | USA | Right | Right | 6' 3" | 210 lbs | - |
| Scarborough, Caden | SP | Plant City Farmers | 20 | 04/01/2005 | Unknown | USA | Right | Right | 6' 5" | 185 lbs | - |
| Schlesinger, Rafe | RP | Dunedin Danger | 22 | 01/22/2003 | Holbrook | USA | Left | Left | 6' 3" | 200 lbs | - |
| Schobel, Tanner | 2B | Gainesville Gators | 23 | 06/04/2001 | Unknown | USA | Right | Right | 5' 10" | 170 lbs | - |
| Sena, Reidis | RP | Dunedin Danger | 24 | 04/07/2001 | Unknown | DOM | Right | Right | 5' 10" | 160 lbs | - |
| Serna, Luis | SP | Lakeland Catfish | 20 | 07/20/2004 | San Luis Río Colorado | MEX | Right | Right | 5' 11" | 145 lbs | - |
| Sharpe, Davis | RP | Plant City Farmers | 25 | 01/30/2000 | Arlington | USA | Right | Right | 6' 4" | 215 lbs | - |
| Simoneit, William | 1B | Vero Beach Blue Angels | 28 | 10/14/1996 | Glen Ellyn | USA | Right | Right | 6' 4" | 235 lbs | - |
| Smith, Jaylen | RP | Daytona Firebirds | 25 | 11/05/1999 | Copperas Cove | USA | Left | Left | 5' 11" | 170 lbs | - |
| Smith, Parker | SP | Vero Beach Blue Angels | 22 | 03/05/2003 | Bellaire | USA | Right | Right | 6' 3" | 230 lbs | - |
| Smith, Shane | RP | Plant City Farmers | 25 | 04/04/2000 | Danvers | USA | Right | Right | 6' 4" | 230 lbs | - |
| Smith, Travis | SP | St. Lucie Sand Gnats | 22 | 11/09/2002 | Walton | USA | Right | Right | 6' 4" | 220 lbs | - |
| Soto, Charlee | SP | Tampa Tigers | 19 | 08/31/2005 | Kissimmee | USA | Switch | Right | 6' 5" | 210 lbs | - |
| Sparks, Wyatt | SP | Tampa Tigers | 25 | 09/27/1999 | Aurora | USA | Right | Right | 6' 2" | 185 lbs | - |
| Spence, Liam | 3B | Lakeland Catfish | 27 | 04/09/1998 | Unknown | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sprague-Lott, Jared | SS | Dunedin Danger | 23 | 10/10/2001 | Philadelphia | USA | Right | Right | 6' 0" | 195 lbs | - |
| Stanley, Hunter | RP | Free Agent | 27 | 08/25/1997 | Hammond | USA | Right | Right | 6' 0" | 190 lbs | - |
| Stowers, Josh | LF | Tampa Tigers | 28 | 02/25/1997 | Westchester | USA | Right | Right | 6' 0" | 200 lbs | - |
| Strong, Jackson | LF | Lakeland Catfish | 21 | 08/26/2003 | West Seneca | USA | Left | Left | 6' 1" | 185 lbs | - |
| Stumpo, Mitchell | RP | Gainesville Gators | 28 | 06/17/1996 | Raleigh | USA | Right | Right | 6' 2" | 205 lbs | - |
| Suisbel, Luis | 3B | Dunedin Danger | 21 | 05/23/2003 | Valencia | VEN | Switch | Right | 6' 1" | 190 lbs | - |
| Swanson, Zach | RP | Lakeland Catfish | 19 | 09/25/2005 | Castle Rock | USA | Right | Right | 6' 3" | 195 lbs | - |
| Sykora, Travis | SP | Plant City Farmers | 20 | 04/28/2004 | Round Rock | USA | Right | Right | 6' 6" | 220 lbs | - |
| Szykowny, Charlie | 3B | St. Lucie Sand Gnats | 24 | 06/30/2000 | Colorado Springs | USA | Left | Right | 6' 4" | 225 lbs | - |
