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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salgado, Bryant | RP | Knoxville Nighthawks | 25 | 03/02/2000 | Unknown | PUR | Right | Right | 6' 1" | 205 lbs | - |
| Salinas, Iziah | RP | Cooperstown Cougars | 20 | 01/25/2005 | Garden City | USA | Left | Left | 6' 1" | 180 lbs | - |
| Sanchez, Carlos | SS | Marion Dukes | 20 | 01/12/2005 | Santo Domingo | DOM | Left | Right | 6' 0" | 175 lbs | - |
| Sanchez, Justin | SP | New River Admirals | 22 | 10/11/2003 | Fort Wayne | USA | Left | Left | 5' 11" | 175 lbs | - |
| Santa Maria, Tony | 3B | Rome Gladiators | 23 | 04/06/2002 | Absecon | USA | Right | Right | 5' 11" | 200 lbs | - |
| Santana, Ruben | 3B | Knoxville Nighthawks | 20 | 02/16/2005 | El Seibo | DOM | Right | Right | 6' 0" | 190 lbs | - |
| Santiago, Chris | RP | Pulaski Ironclads | 24 | 06/18/2001 | Unknown | USA | Right | Right | 6' 2" | 205 lbs | - |
| Santos, Lisandro | RP | Savannah Sand Gnats | 27 | 07/24/1998 | Santiago | DOM | Left | Left | 6' 1" | 180 lbs | - |
| Scalzo, Frankie | RP | Atlantic City Caesars | 26 | 08/25/1999 | San Diego | USA | Right | Right | 6' 3" | 185 lbs | - |
| Schanaman, Shay | RP | Virginia Beach Hurricanes | 26 | 08/12/1999 | Grand Island | USA | Right | Right | 6' 0" | 205 lbs | - |
| Schanuel, Brady | RP | Johnson City Eagles | 28 | 02/21/1997 | Belleville | USA | Right | Right | 6' 3" | 180 lbs | - |
| Schiavone, Jason | C | Kingsport Arsenal | 22 | 03/19/2003 | Unknown | USA | Right | Right | 6' 2" | 205 lbs | - |
| Schiefer, Ryan | RP | Rome Gladiators | 22 | 08/19/2003 | Gilbert | USA | Right | Right | 6' 3" | 170 lbs | - |
| Schrand, Jake | RP | Pulaski Ironclads | 26 | 08/08/1999 | Cincinnati | USA | Right | Right | 6' 0" | 180 lbs | - |
| Schultz, Andrew | RP | Knoxville Nighthawks | 28 | 07/31/1997 | Alpharetta | USA | Right | Right | 6' 4" | 195 lbs | - |
| Schwartz, Gary | RF | Pulaski Ironclads | 29 | 01/22/1996 | Unknown | USA | Left | Left | 6' 1" | 215 lbs | - |
| Scull, Anthony | CF | Jackson Generals | 21 | 01/26/2004 | Havana | CUB | Left | Left | 6' 0" | 165 lbs | - |
| Sears, Andrew | SP | Pulaski Ironclads | 23 | 10/30/2002 | West Warwick | USA | Left | Left | 6' 3" | 200 lbs | - |
| Severino, Anderson | RP | Asheville Aviators | 31 | 09/17/1994 | Unknown | DOM | Left | Left | 5' 10" | 165 lbs | - |
| Shaw, Sam | LF | Chattanooga Wildcats | 20 | 02/26/2005 | Victoria | CAN | Right | Right | 5' 10" | 180 lbs | - |
| Shepardson, Blake | 1B | Atlantic City Caesars | 22 | 07/06/2003 | Highlands Ranch | USA | Right | Right | 6' 6" | 200 lbs | - |
| Shirk, Jake | RP | New River Admirals | 23 | 06/05/2002 | Fort Wayne | USA | Right | Right | 6' 2" | 200 lbs | - |
| Shoemaker, Adam | SP | Free Agent | 23 | 08/24/2002 | Cambridge | CAN | Left | Left | 6' 6" | 205 lbs | - |
| Shreve, Chasen | RP | Chattanooga Wildcats | 35 | 07/12/1990 | Las Vegas | USA | Left | Left | 6' 3" | 180 lbs | - |
| Sightler, Josiah | RP | Marion Dukes | 26 | 10/19/1999 | Unknown | USA | Left | Left | 6' 5" | 235 lbs | - |
| Silva, Eric | RP | Pikeville Polecats | 23 | 08/03/2002 | Baldwin Park | USA | Right | Right | 6' 1" | 185 lbs | - |
| Silva, William | RP | Free Agent | 24 | 08/02/2001 | Unknown | USA | Right | Right | 6' 0" | 180 lbs | - |
| Sim, Kevin | 3B | Knoxville Nighthawks | 23 | 02/07/2002 | San Diego | USA | Right | Right | 6' 2" | 210 lbs | - |
| Sinacola, Nick | RP | Pikeville Polecats | 26 | 08/29/1999 | Providence | USA | Left | Right | 6' 1" | 190 lbs | - |
| Sinatro, Danny | CF | New River Admirals | 28 | 09/18/1997 | Sammamish | USA | Left | Right | 6' 0" | 180 lbs | - |
| Sinnard, Luke | SP | Virginia Beach Hurricanes | 23 | 10/21/2002 | Hendersonville | USA | Right | Right | 6' 8" | 250 lbs | - |
| Smith, Austin | SP | Virginia Beach Hurricanes | 26 | 06/22/1999 | Cedar Park | USA | Right | Right | 6' 3" | 200 lbs | - |
| Smith, Chad C. | RP | Pikeville Polecats | 30 | 06/08/1995 | Bessemer | USA | Right | Right | 6' 4" | 205 lbs | - |
| Smith, Milton | LF | Free Agent | 28 | 09/25/1997 | Starkville | USA | Left | Left | 5' 10" | 165 lbs | - |
| Smith, Parker | SP | Cooperstown Cougars | 22 | 03/05/2003 | Bellaire | USA | Right | Right | 6' 3" | 230 lbs | - |
| Sommers, Jake | RP | Pikeville Polecats | 28 | 05/05/1997 | Hortonville | USA | Right | Right | 6' 2" | 190 lbs | - |
| Soularie, Alerick | CF | Free Agent | 26 | 07/05/1999 | Houston | USA | Right | Right | 6' 0" | 175 lbs | - |
| Sprague, Shea | SP | Virginia Beach Hurricanes | 22 | 01/03/2003 | Hanover | USA | Right | Left | 6' 3" | 185 lbs | - |
| Stainbrook, Troy | RP | Cooperstown Cougars | 29 | 10/31/1996 | Visalia | USA | Left | Left | 6' 6" | 250 lbs | - |
| Standlee, Brett | RP | Pikeville Polecats | 27 | 09/14/1998 | Tulsa | USA | Right | Right | 6' 4" | 225 lbs | - |
| Statler, Tyler | RP | Pikeville Polecats | 24 | 07/01/2001 | Roscoe | USA | Right | Right | 6' 6" | 230 lbs | - |
| Steels, Jacob | RF | Jackson Generals | 23 | 06/17/2002 | Santa Maria | USA | Right | Right | 6' 0" | 185 lbs | - |
| Steinmetz, Jacob | RP | Chattanooga Wildcats | 22 | 02/19/2003 | Queens | USA | Right | Right | 6' 5" | 220 lbs | - |
| Sterling, Levi | SP | Jackson Generals | 19 | 09/02/2006 | Los Angeles | USA | Right | Right | 6' 5" | 205 lbs | - |
| Stumbo, Peyton | RP | Cooperstown Cougars | 23 | 02/16/2002 | Auburn | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sublette, Ryan | RP | New River Admirals | 27 | 08/01/1998 | Chicago | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sulser, Cole | RP | Asheville Aviators | 35 | 03/12/1990 | San Diego | USA | Right | Right | 6' 0" | 195 lbs | - |
| Swain, Matthew | RP | Knoxville Nighthawks | 28 | 08/20/1997 | Stone Mountain | USA | Right | Right | 6' 7" | 225 lbs | - |
| Swanson, Nic | RP | Knoxville Nighthawks | 26 | 02/08/1999 | Tulsa | USA | Right | Right | 6' 2" | 180 lbs | - |
| Swiney, Nick | RP | Asheville Aviators | 26 | 02/12/1999 | Nashville | USA | Right | Left | 6' 3" | 185 lbs | - |
